99% Purity Raw Material Powder Ivermectin Veterinary Drug Ivermectin Powder Insecticide Ivermectin
China 99% Purity Raw Material Powder Ivermectin Veterinary Drug Ivermectin Powder Insecticide Ivermectin, Find details about China CAS 70288-86-7 Ivermectin, USP 99% Ivermectin from 99% Purity Raw Material Powder Ivermectin Veterinary Drug Ivermectin Powder Insecticide Ivermectin
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99% Purity Raw Material Powder Ivermectin Veterinary Drug Ivermectin powder Insecticide Ivermectin
Product Name:Ivermectin
CAS:70288-86-7
Einecs No:274-536-0
Appearance:White crystalline powder
MF:C95H146O28
Molecular Weight:1736.16
Purity:99%
Shelf Life:24 Months
Ivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod,
canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum resistant parasites.
Ivermectin for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae
effectively, but for adult worms; For only in intestinal fecal round worms are also effective.
Ivermectin has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid chlorin ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane, cause nerve cells or muscle cells hyperpolarization, parasites paralysis or death.
| Product Name | lvermectin | Manufacture Date | April10,2021 | |
| Batch No. | WU210410 | certificate Date | April 13,2021 | |
| Batch Quantity | 560KG | Expiration Date | April 09,2023 | |
| ltems | Specifications | Results | ||
| Appearance | White or yellowish-white crystalline powder, slightly hygroscopic | Complies | ||
| Solubility | Practically insoluble in water, freely soluble in methylene chlorid, soluble in alcohol | Complies | ||
| ldentification | IR | Corresponds with that of CRS standard | Complies | |
| HPLC | The retention time for HzBla and HB1 in chromatogram obtained with the best solution corresponds to those of standard preparation | Complies | ||
| Appearance of solution | Clear and not more intensely colored than BYz | Complies | ||
| Specific optical rotation (anhydrous and solvent-free substance) | -20~-17° | -17.7° | ||
| Related substances(%) | Individual impurities(BRT1.3-1.5)2.5 | L-1:<0.05 K:2.1 | ||
| Any other impurities≤1 | c:0.05 A:0.58 J:0.21 H:0.31 D:0.05F:<0.05 E:0.53-2:0.17 RTS1,09:0.08 | |||
| Totals5 | 4 | |||
| Disregard limit:0.05 | ||||
| Ethanol and Formamide(%) | Ethanol<5.0 | 3.9 | ||
| Formamides3.0 | 2.6 | |||
| Heavy metal(%) | s0.002 | <0.002 | ||
| Water(%) | ≤1.0 | 0.14 | ||
| Catalyst(ugg) | S1 | <1 | ||
| Sulphated ash(%) | ≤0.1 | 0.05 | ||
| Assay(%) (HPLC, on dry basis) | HB13JH4aB1+H>B15) 290.9 | 98.1 | ||
| 95.gSHB4HB1a102.0 | 96 | |||
| Conclusion | omplies with the requirements of EP 9.0 | |||
Function
1. Ivermectin is the derivatives of abamectin. Ivermectin belongs to oral semisynthetic broad-spectrum drug resistant parasites.
2. Ivermectin has effect for most of the various life cycle nematodes.
3. Ivermectin has effect for the microfilaria of onchocerca volvulus,but it does not has effect for the adult onchocerca volvulus
4. Ivermectin has effect for dung round worms that is only stay in intestinal tract
5. Ivermectin has selective inhibition.
6. Ivermectin can not go through the blood brain barrier of humanbeings
In veterinary medicine ivermectin is used against many intestinal worms (but not tapeworms), most mites, and some lice. Despite this, it is not effective for eliminating ticks, flies, flukes, or fleas. It is effective against larval heartworms, but not against adult heartworms, though it may shorten their lives. The dose of the medicine must be very accurately measured as it is very toxic in over-dosage.
It is sometimes administered in combination with other medications to treat a broad spectrum of animal parasites. Some dog breeds (especially the Rough Collie, the Smooth Collie, the Shetland Sheepdog, and the Australian Shepherd), though, have a high incidence of a certain mutation within the MDR1 gene (coding for P-glycoprotein); affected animals are particularly sensitive to the toxic effects of ivermectin.
Clinical evidence suggests kittens are susceptible to ivermectin toxicity. A 0.01% ivermectin topical preparation for treating ear mites in cats (Acarexx) is available.
Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray. While this works well in some cases, care must be taken, as several species of reptiles are very sensitive to ivermectin. Use in turtles is particularly contraindicated.
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Xi'an Wucine Bio Industries Inc is a national key high-tech enterprise,which mainly specializes in the R&D,operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access.Our company has independent R&D center,raw material synthesis workshop,has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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