China Supply Antihistamine Powder CAS 113-92-8 Chlorphenamine Maleate, Find details about China Chlorphenamine, Chlorphenamine Maleate from Supply Antihistamine Powder CAS 113-92-8 Chlorphenamine Maleate
Product Name | Chlorpheniramine Maleate |
Other Name | Chlorphenamine |
CAS No. | 113-92-8 |
Einecs No. | 204-037-5 |
Appearance | White Powder |
Speccification | 99% |
Molecular formula | C20H23ClN2O4 |
MOQ | 1kg |
Application | Medicine |
Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an ischemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemiareperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.
Specification
TEST ITEMS | SPECIFICATION | RESULTS |
Description | White Or Almost White Crystalline Powder | White Powder |
Identification | Infrared Absorption | Positive |
Assay | 97.0~103.0% | 99.2% |
Melting Point | 33~37ºC | 34.5~36.5ºC |
Loss On Drying | 0.5%max | 0.30% |
Organic Volatile Impurities | 2500PPm max | <1000PPm |
Residual Solvents | Meet the requirements.(USP29) | Confirms |
Chromatographic purity | sum of impurities:3.0%max | <3.0% |
Conclusion | The specification conform with USP32 standard |
Package & Delivery
By Express | By Air | By Sea | ||
Suitable for under 50kg Fast: 3-7 days High cost Door to door service, easy to pick up the goods | Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed | Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed |