Kir4.1 Polyclonal Antibody

China Kir4.1 Polyclonal Antibody, Find details about China Antibody, Protein from Kir4.1 Polyclonal Antibody

Model NO.
BS60116-B
Trademark
Bioworld
Specification
100ug/1mg
Origin
China
Model NO.
BS60116-B
Trademark
Bioworld
Specification
100ug/1mg
Origin
China
Catalog No.BS60116-B
Product NameKIR4.1 polyclonal antibody
ApplicationsWB IHC
Alternative NameATP-sensitive inward rectifier potassium channel 10; ATP-dependent inwardly rectifying potassium channel Kir4.1; Inward rectifier K(+) channel Kir1.2; Potassium channel, inwardly rectifying subfamily J member 10; KCNJ10
Swiss-ProtP78508
HostRabbit
ReactivityHuman,Rat,Mouse
Application_allWB: 1:500~1:2000 IHC: 1:50~1:100
ProductRabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Purification&PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&StabilityStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SpecificityKIR4.1 polyclonal antibody detects endogenous levels of KIR4.1 protein.
BiowMW~ 45 kDa
NoteFor research use only, not for use in diagnostic procedure.
ImmunogenSynthetic peptide, corresponding to Human KIR4.1.

  • Western blot (WB) analysis of KIR4.1 polyclonal antibody at 1:2000 dilution Lane1:HEK293T whole cell lysate(40ug) Lane2:The Kidney tissue lysate of Rat(40ug) Lane3:The Brain tissue lysate of Mouse(40ug)

  • Immunohistochemistry of paraffin-embedded Human Kidney cancer tissue using KIR4.1 antibody at dilution of 1:20 (x40 lens).

Background

The KIR (for inwardly rectifying potassium channel) family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. KIR4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. KIR4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human KIR4.1 maps to chromosome 1. KIR4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human KIR4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and KIR4.2 may play a role in the pathogenesis of Down's syndrome. KIR5.1 forms functional channels only by coexpression with either KIR4.1 or KIR4.2 in the kidney and pancreas.Kir4.1 Polyclonal AntibodyKir4.1 Polyclonal Antibody
Kir4.1 Polyclonal AntibodyKir4.1 Polyclonal AntibodyKir4.1 Polyclonal AntibodyKir4.1 Polyclonal Antibody