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Wholesale China Factory Price Provide Samples Benzocaine/ Procaine / Tetracaine/ Levamisole/ Lidocaine/ Boric Flakes CAS 94-09-7 Benzocaine

Wholesale China Factory Price Provide Samples Benzocaine/ Procaine / Tetracaine/ Levamisole/ Lidocaine/ Boric Flakes CAS 94-09-7 Benzocaine, Find details about China Benzocaine, Benzocaine Powder from Wholesale China Factory Price Provide Samples Benzocaine/ Procaine / Tetracaine/ Levamisole/ Lidocaine/ Boric Flakes CAS 94-09-7 Benzocaine

Model NO.
HD-22
Trademark
No
Transport Package
Boxes
Origin
China
Model NO.
HD-22
Trademark
No
Transport Package
Boxes
Origin
China
Wholesale China Factory Price Provide Samples Benzocaine/ Procaine / Tetracaine/ Levamisole/ Lidocaine/ Boric Flakes CAS 94-09-7 Benzocaine
Product Description
 
Boiling Point350.8ºC at 760 mmHg
Melting Point80-82°C
Molecular FormulaC14H23ClN2O
Molecular Weight270.798
Flash Point166ºC
Exact Mass270.149902
PSA32.34000
LogP3.45870
Storage conditionRefrigerator

Application :

Lidocaine Hcl salt, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx. Lidocaine is a common local anesthetic and antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery. Lidocaine, the first amino amide-type local anesthetic, was first synthesized under the name xylocaine by Swedish chemist Nils Lofgren in 1943. His colleague Bengt Lundqvist performed the first injection anesthesia experiments on himself. Lidocaine is approximately 95% metabolized (dealkylated) in the liver by CYP3A4 to the pharmacologically-active metabolites monoethylglycinexylidide (MEGX) and then subsequently to the inactive glycine xylidide. MEGX has a longer half life than lidocaine but also is a less potent sodium channel blocker. The elimination half-life of lidocaine is approximately 90-120 minutes in most patients. This may be prolonged in patients with hepatic impairment (average 343 minutes) or congestive heart failure (average 136 minutes).

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