China Ifn Beta Polyclonal Antibody, Find details about China Antibody, Protein from Ifn Beta Polyclonal Antibody
Catalog No. | BS62219 |
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Product Name | IFN beta polyclonal antibody |
Applications | WB IHC |
Alternative Name | Interferon beta; Interferon β; IFN-beta; IFN-β; IFNβ; Fibroblast interferon; IFB; IFNB |
Swiss-Prot | P01574 |
Host | Rabbit |
Reactivity | Human,Mouse,Rat |
Application_all | WB: 1:500~1:1000 |
Product | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Purification&Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
Storage&Stability | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Specificity | IFN beta polyclonal antibody detects endogenous levels of IFN beta protein. |
BiowMW | ~ 22 kDa |
Note | For research use only, not for use in diagnostic procedure. |
Immunogen | Synthetic peptide, corresponding to Human IFN beta. |
Background
The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, one IFN-β gene, one IFN-w (also known as IFN-α II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent antiviral activity. IFN-α and -β exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a multisubunit receptor.