Isoquercetin are found not only in foods such as apple and onion, but in many medicinal plants,Isoquercetin is a flavonoid, a type of chemical compound. It is the 3-O-glucoside of quercetin. Isoquercetin can be isolated from various plant species including mango and Rheum nobile.
Rhein has anti-tumor activity, antibacterial activity, immunosuppression, diuresis, diarrhea, anti-inflammation, and treatment of diabetes and nephropathy. Health products are mainly used for reducing fat and weight, relaxing bowels and expelling toxin, cleaning the internal environment, preventing gastric cancer and delaying aging. 

As an effective antioxidant, it is used as natural raw materials of cosmetics. For example, it can be added to the body and facial moisturizing cream, sunscreen products and other cosmetics. Besides, it can be added to the products as a function of anti-wrinkle.
It has a protective effect on inflammation, cardiovascular disease, allergies, neurological diseases and other chronic diseases and has been applied to food and beverages as supplements.

1. Rhein  is shown to improve digestion and increase the appetite.
2. Rhein  also helps heal ulcers, alleviate disorders of the spleen and colon, relieve constipation and help heal hemorrhoids and bleeding in the upper digestive tract. 3. Anti tumor activity and antibacterial activity also have immunosuppression, cathartic and anti-inflammatory effection.
3. As the raw materials of drugs for cooling blood, detoxification and relaxing the bowels, it is mainly used in pharmaceutical field;
4. As products for improving blood circulation and treating amenorrhea , Rhein is mainly used in health product industry.