China API Anti Aging CAS 1094-61-7 Nmn Price 99% Nicotinamide Mononucleotide Powder Raw Material Nmn, Find details about China Beta Nmn, Nmn Powder from API Anti Aging CAS 1094-61-7 Nmn Price 99% Nicotinamide Mononucleotide Powder Raw Material Nmn
Product Name: Nicotinamide Mononucleotide
Appearance: White powder
Purity:98%
Molecular Weight: 334.22
CAS NO:1094-61-7
M.F. C11H15N2O8P
Nicotinamide mononucleotides play an important role in the production of human cell energy, which is involved in the synthesis of intracellular NAD (nicotinamide adenine dinucleotide, an important coenzyme for cell energy conversion).
Nicotinamide Mononucleotide belongs to Vitamin B, participating in metabolism in the body, can be used to prevent pellagra or other niacin defection disease.
Nicotinamide Mononucleotide could be used as feed/human nutrition, booth the growth and strengthen the immunity.
Nicotinamide mononucleotide ("NMN" and "β-NMN") is a nucleotide derived from ribose and nicotinamide.
Niacinamide (nicotinamide) is a derivative of vitamin B3, also known as niacin. As a biochemical precursor of NAD+, it may be useful in the prevention of pellagra.
Its precursor, niacin, is found in a variety of nutritional sources: peanuts, mushrooms (portobello, grilled), avocados, green peas (fresh), and certain fish and animal meats.
In studies on mice, NMN has shown to reverse age-related arterial dysfunction by decreasing oxidative stress. A long-term study indicates that NMN can slow down the physiologic decline in ageing mice. As a result, the older mice in the study have metabolism and energy levels resembling those of younger mice, with extended life spans. However, NMN did not show similar beneficial effects in young mice.The anti-ageing properties are being tested on humans in Japan.
Appliction
The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca2+ signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.
NMNAT1 is the most widely expressed of three orthologous genes with nicotinamide-nucleotide adenylyltransferase (NMNAT) activity. Genetically engineered mice lacking NMNAT1 die during early embryogenesis, indicating a critical role of this gene in organismal viability.[citation needed] In contrast, mice lacking NMNAT2, which is expressed predominantly in neural tissues, complete development but die shortly after birth. However, NMNAT1 is dispensable for cell viability, as homozygous deletion of this gene occurs in glioblastoma tumors and cell lines. NMNAT enzymatic activity is probably essential at the cellular level, as complete ablation of NMNAT activity in model organisms leads to cellular inviability.
Function
Nicotinamide Mononucleotide NMN belongs to Vitamin B, participating in metabolism in the body, can be used to prevent pellagra or other
niacin defection disease.
Nicotinamide Mononucleotide NMN could be used as feed/human nutrition, booth the growth and strengthen the immunity.
ANALYSIS | SPECIFICATION | RESULT |
Appearance: | White to yellowish powder | White powder |
Purity : | NLT 98.00 % by HPLC | 99.56 % |
Water content(KF): | NMT 5.0 % | 0.2 % |
Residual solvent: | ETOH NMT 2.0% | Complies |
Sodium content: | NMT 1.0 % | Complies |
Plumbum: | NMT 0.5 ppm | Complies |
Mercury: | NMT 0.5 ppm | Complies |
Cadmium: | NMT 0.5 ppm | Complies |
Total plate count: | NMT 750 cfu/g | Complies |
E.coli: | NMT 3 MPN/g | Complies |
Packing
25kgs/Fiber drum outside and plastic bag inside;
1-25kgs packaging, aluminium Foil bag outside and double plastic bag inside;
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