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Wuhan Hhd Maxacalcitol (22-Oxacalcitriol)) CAS No. 103909-75-7 with High Purity 99.0%Min. Small Molecule Compounds Hyperparathyroidism, Psoriasis

China Wuhan Hhd Maxacalcitol (22-Oxacalcitriol)) CAS No. 103909-75-7 with High Purity 99.0%Min. Small Molecule Compounds Hyperparathyroidism, Psoriasis, Find details about China Maxacalcitol, CAS 103909-75-7 from Wuhan Hhd Maxacalcitol (22-Oxacalcitriol)) CAS No. 103909-75-7 with High Purity 99.0%Min. Small Molecule Compounds Hyperparathyroidism, Psoriasis

Color
White
Grade
Pharmaceutical Grade
Trademark
hhdpharm
Specification
10g, 50g, 200g, 1kg, 5kg
Origin
China
Color
White
Grade
Pharmaceutical Grade
Trademark
hhdpharm
Specification
10g, 50g, 200g, 1kg, 5kg
Origin
China
What is Vitamin D Derivative Drugs?

Active vitamin D drugs are a general term for a series of vitamin D2/D3 derivatives, commonly referred to as "calciferol" drugs. These compounds are complex in structure and involve techniques such as photochemistry and microbial transformation. They are difficult to synthesize, sensitive to light and oxygen, and the API in the preparation is microgram-level, and the development threshold is high. Clinically used mainly for the treatment of osteoporosis, secondary hyperparathyroidism and psoriasis.

Description

Maxacalcitol is the third synthetic vitamin D analog, after paricalcitol and doxercalciferol, to be marketed for the treatment of secondary hyperparathyroidism (SHPT) associated with chronic renal failure. It is a new vitamin D3 derivative with an oxygen atom in 22-position as main structural feature (22-oxacalcitriol, OCT). This vitamin D receptor agonist has a strong inhibitory effect on synthesis and secretion of parathyroid hormone in the setting of severe parathyroid hyperplasia. Maxacalcitol induced only minor effects on calcium and phosphate metabolism unlike an agent such as 1, 25(OH)2D3 that produced hypercalcemia and hyperphosphatemia.

Maxacalcitol Basic information 
 
Product Name:
Maxacalcitol
 
Synonyms:(5Z,7E)-9,10-Seco-22-oxacholesta-5,7,10(19)-triene-1α,3β,25-triol;
22-Oxa-1α,25-dihydroxycholecalciferol;
Oxacalcitriol;
(+)-(5Z,7E)-(1S,3R,20S)-20-(3-Hydroxy-3-methylbutyloxy)-9,10-secopregna-5,7,10(19)-triene-1,3-diol;
1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-;
(1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol;
4-methylene-5Z-[2E-[(3aS)-octahydro-1S-[1S-(3-hydroxy-3-methylbutoxy)ethyl]-7aS-methyl-4H-inden-4-ylidene]ethylidene]-1R,3S-cyclohexanediol
CAS:103909-75-7
MF:C26H42O4
MW:418.61
Mol File:103909-75-7.mol
Quality Standard:Internal Standard
Molecular Structure:High Purity 99% Quality CAS 103909-75-7 Maxacalcitol Raw Material Powder with Reasonable Price
 
Maxacalcitol Chemical Properties
 
Melting point 122°
Alpha D20 +49.4° (c = l.00 in ethanol)
Storage temp. Store at -20°C
 
High Purity 99% Quality CAS 103909-75-7 Maxacalcitol Raw Material Powder with Reasonable Price
Maxacalcitol Usage
 
Maxacalcitol is the noncalcemic analogue of vitamine D and was found to suppress parathyroid hormone synthesis and secretion.

 

Only for Research & Lab Use,not for human use.
We also supply the following small molecule chemical compounds as follows:
Calcipotriol CAS No. 112965-21-6 with High Purity 99.0%Min. Small Molecule Compounds Psoriasis
Calcipotriol CAS No. 112965-21-6 with High Purity 99.0%Min. Small Molecule Compounds Psoriasis

Calcipotriol CAS No. 112965-21-6 with High Purity 99.0%Min. Small Molecule Compounds Psoriasis


Calcipotriol CAS No. 112965-21-6 with High Purity 99.0%Min. Small Molecule Compounds Psoriasis
Calcipotriol CAS No. 112965-21-6 with High Purity 99.0%Min. Small Molecule Compounds Psoriasis

Wuhan Hhd Maxacalcitol (22-Oxacalcitriol)) CAS No. 103909-75-7 with High Purity 99.0%Min. Small Molecule Compounds Hyperparathyroidism, Psoriasis

 

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