China 2019 Hot Sale Pharmaceutical Medecine Rabeprazole Sodium CAS No. 117976-90-6, Find details about China Rabeprazole Sodium, 99% Purity Rabeprazole Sodium from 2019 Hot Sale Pharmaceutical Medecine Rabeprazole Sodium CAS No. 117976-90-6
Rebeprazole sodium Chemical & Physical Properties
Name: Rebeprazole sodium
Test Method: HPLC
Purity: ≥99%
CAS No.:117976-90-6
Mol. Formula:C18H20N3NaO3S
Mol. Weight:381.42447
Rabeprazole sodium azole canker is a proton pump inhibitor class taking the drugs, for ray Bella azole sodium salt form, first by the Japanese Eisai company successfully developed for the first time, name of commodity for wave force, the role of proton pump inhibitors is to reduce gastric acid secretion of stable disease areas, so as to cure the stomach and duodenal ulcers and stomach esophagus regurgitation disease effect. It is mainly used in clinical treatment of acid-related diseases, such as gastric and duodenal ulcer selection, peptic ulcer, gastroesophageal reflux disease, zhuoye syndrome and so on.
Rabeprazole is a benzimidazole substitute that inhibits gastric acid secretion by binding to the proton pump of gastric parietal cells. This product inhibits the action of adenosine triphosphate, a key enzyme in the production of gastric acid. It can inhibit the secretion of basic gastric acid and gastric acid caused by stimulation.
Rabeprazole is a white to yellowish-white powder with no odor and a molecular weight of 381.43. It is easily soluble in water or methanol, anhydrous ethanol or ethyl acetate, almost insoluble in ether or ethane. This product does not display the optical activity, absorption temperature resistance, its melting point is 225 ºC, the pH value of 7.0 of the distribution coefficient of water/octane is about 214. This product is a light yellow film coated tablet (enteric-coated tablet).
Adverse reactions and precautions: gastric cancer should be excluded after the use of this drug. Adverse reactions include anaphylaxis, palpitations, constipation, diarrhea, headache, edema, leukopenia, AST, ALT, elevated total bilirubin, and proteinuria. The combination of rabeprazole sodium and digoxin can increase the concentration of digoxin. Do not use with antacids. Patients with a history of drug allergy, cirrhosis of the liver, the elderly, pregnant and lactating women, children with caution.
Rebeprazole sodium is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions caused by excess stomach acid. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Rebeprazole sodium Specification
Characters | White to pale yellowish white powder. | White to pale yellowish white powder. | |
Solubility | It is very soluble in water, and freely soluble in ethanol. | Very soluble in water and methanol, freely soluble in ethanol, practically insoluble in ether. | |
Identification
| UV | Both spectra exhibit similar intensities of absorption at the same wavelengths | It exhibits maximum absorption at the wavelength of 292nm. |
IR | Both spectra exhibit similar intensities of absorption at the same wave numbers | Both spectra exhibit similar intensities of absorption at the same wave numbers | |
Sodium Salt Reaction | A solution of Rabeprazole Sodium (1 in 10) responds to the Qualitative Tests <1.09>for sodium salt. | It responds to the Qualitative Tests for sodium salt. | |
Chromogenic reaction | The solution turns to orange. |
| |
Heavy metals | Not more than 10ppm | Not more than 10ppm | |
Color and clarity of solution | Not darker than Reference Solution H. |
| |
Related substances | Individual impurity <0.1% Total impurities < 1.0% | Total impurities < 1.5%
| |
Loss on drying | Not more than 1.0% | Not more than 1.0% | |
Residual solvents | Dichloromethane<600ppm Acetone < 5000ppm Ethyl Acetate < 5000ppm Anhydrous alcohol<5000ppm
| Dichloromethane < 600ppm Acetone < 5000ppm Ethyl Acetate < 5000ppm Anhydrous alcohol < 5000ppm
| |
Assay | 98.0%-101.0% | Not less than 98.0% |
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1)Products can be sent out in 3 days after payment. Tracking number available, fixed service person are 7x24h for you to contact.
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Packing: Refer the picture
1. 25kg/drum : 25kg net weight,28kg gross weight; Packed in a cardboard-drum with two plasticbags insideSize: 510mm high, 350mm diameter
2. 1kg/bag (1kg net weight, 1.2kg gross weight, packed in an aluminum foil bag) OR as per your request.
1,High quality and competetive price. we can offer COA Certificate and official Invoice;
2,We are manufacturer, products plenty in stock and orders can be delivered in the first time;
Products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (SGS/ CTI/ ITS), only after your confirmation will we send it out to you.
3,Rich experienced packing and delivery department,packages well disguised,fast and safe delivery, pass rate above 99%;
4,Express company:EMS,HKEMS,Fedex,TNT,UPS,DHL etc;
5,We have reship policy if parcel can't reach your hands due to custom;
6,24/7 online after-sales service
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