China Material Antibiotic Doxycycline HCl Doxycycline Hydrochloride 10592-13-9, Find details about China Doxycycline HCl Powder, Veterinary Doxycycline HCl from Material Antibiotic Doxycycline HCl Doxycycline Hydrochloride 10592-13-9
Product Name | Doxycycline HCl |
CAS | 10592-13-9 |
Appearance | Yellow crystalline powder |
MF | C22H25ClN2O8 |
Molecular Weight | 480.9 |
Purity | 99% min |
Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder |
Shelf Life | 24 Months |
Items | Specifications | Results |
Appearance | Yellow crystalline powder | Conforms |
Identification | TLC | Conforms |
sulphuric acid reaction a yellow colour develops | Conforms | |
it gives reaction of chlorides | Conforms | |
PH | 2.0~3.0 | 2.3 |
Specific absorbance | at 349nm e(1%) 300~355 | 320 |
Specific optical rotation | -105 ~ -120° | -110° |
Heavy metals: | ≤50ppm | < 20ppm |
Light-absorbing impurities | at 490nm ≤0.07 | 0.03 |
Related substances | 6-epidoxycycline ≤2.0% metacycline ≤2.0% 4-epidoxycycline ≤0.5% (ep5) 4-epi-6-epidoxycycline ≤0.5% (ep5) oxytetracycline ≤0.5% (ep5) any other impurity ≤0.5% not identified impurities ≤0.1% (ep5) | 1.6% 0.1% Not found Not found Not found Not found Not found |
Ethanol | 4.3~6.0% (m/m) | 4.5% |
Sulphated ash | ≤0.4% | 0.05% |
Water | 1.4~2.8% | 1.8% |
Assay | 95.0~102.0% ( c22h25cln2o8) based on anhydrous, ethanol-free substance | 99.2% |
Conclusion | Conform with USP32 |
It is mainly used for upper respiratory tract infection, tonsillitis, biliary tract infection, lympsitis, cellulitis, chronic bronchitis in the elderly caused by sensitive gram-positive cocci and gram-negative bacilli, as well as typhus, scrub typhus, mycoplasma pneumonia, etc.It can be used to treat cholera as well as to prevent falciparum malaria and leptospirosis.
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