Anti -S6K1 Rabbit Polyclonal Primary Antibodies
China Anti -S6K1 Rabbit Polyclonal Primary Antibodies, Find details about China Primary Antibody, Primary Antibodies from Anti -S6K1 Rabbit Polyclonal Primary Antibodies
Anti -S6K1 Rabbit Polyclonal Primary Antibodies
Product Information| Description | S6K1 rabbit polyclonal |
| Protein full name | Ribosomal protein S6 kinase beta-1 |
Synonyms | S6K-beta-1, S6K1, P70S6K1, S6K, Ribosomal protein S6 kinase I, p70 S6 kinase alpha, Rps6kb1, 70 kDa ribosomal protein S6 kinase 1 |
| Immunogen | Recombinant protein corresponding to Mouse S6K1 |
Isotype | IgG |
Purity | Affinity purification |
Predicted MW. | 59 kDa |
Observed MW. | 70 kDa |
| Uniprot ID | P23443, Q8BSK8, P67999 |
Applications
| Applications | WB |
| Species | Human, Mouse, Rat |
| Dilution | 1: 500-1: 1000 |
| Positive tissue | brain, testis |
Background
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex.
Images
| Western blot analysis of S6K1 (GB111133) at dilution of 1: 1000 |
Storage
Storage | Store at -20 ºC for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
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