Primary Antibody Anti -Gba Rabbit Pab

China Primary Antibody Anti -Gba Rabbit Pab, Find details about China Primary Antibody, Antibodies from Primary Antibody Anti -Gba Rabbit Pab

Basic Info.

Model NO.

GB111110

Model No

GB111110

Size

100UL

Sterilization

Pre-Sterile with Radiation

Concentration

1mg/1ml

Instrument Classification

Class I

Type

Pathological Analysis Equipments

Host Animal

Rabbit

Isotype

Igg

Application

Ihc, If

Storage

-20ºC

Package

Bottle with Ice, Individual Foil Pouch

Samples

Available

Species

Mouse, Rat

Trademark

Servicebio

Transport Package

Standard Export Carton

Specification

100ul/pc

Origin

Wuhan, China

HS Code

3502900000

Model NO.

GB111110

Model No

GB111110

Size

100UL

Sterilization

Pre-Sterile with Radiation

Concentration

1mg/1ml

Instrument Classification

Class I

Type

Pathological Analysis Equipments

Host Animal

Rabbit

Isotype

Igg

Application

Ihc, If

Storage

-20ºC

Package

Bottle with Ice, Individual Foil Pouch

Samples

Available

Species

Mouse, Rat

Trademark

Servicebio

Transport Package

Standard Export Carton

Specification

100ul/pc

Origin

Wuhan, China

HS Code

3502900000

Product Desciption

Primary Antibody Anti -GBA Rabbit pAb

Product Information

Description	GBA rabbit polyclonal
Protein full name	Lysosomal acid glucosylceramidase
Synonyms	GBA, GBA1, GCB, GLUC, glucosylceramidase beta, Glucocerebrosidase
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse GBA
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Uniprot ID	P17439

Applications

Applications	IHC	IF
Species	Mouse, Rat	Mouse, Rat
Dilution	1: 1000-1: 2000	1: 500-1: 1000
Positive tissue	kidney, stomach, small intestine, fetal rat	kidney, stomach, small intestine, fetal rat

Background

The GBA is a glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism . May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol . The short chain saturated C8:0-GlcCer and the mono-unsaturated C18:0-GlcCer being the most effective glucose donors for that transglucosylation reaction. Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl-beta-D-glucoside to ceramide. Finally, may also hydrolyze cholesteryl-beta-D-glucoside to produce D-glucose and cholesterol.

Images

	Immunohistochemistry analysis of paraffin-embedded mouse kidney using GBA (GB111110) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat kidney using GBA (GB111110) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded mouse stomach using GBA (GB111110) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded rat small intestine using GBA (GB111110) at dilution of 1: 2000
	Immunohistochemistry analysis of paraffin-embedded mouse fetal rat using GBA (GB111110) at dilution of 1: 2000

Storage

Storage	Store at -20 ºC for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

Primary Antibody Anti -Gba Rabbit Pab