China L-Cystine 56-89-3//Dl-Alanine 302-72-7//L-Leucine 61-90-5//Glycine 56-40-6//Zinc Glycinate 7214-08-6//Dl-Phenylalanine 150-30-1//556-50-3 Glycylglycine, Find details about China Glycylglycine, 556-50-3 from L-Cystine 56-89-3//Dl-Alanine 302-72-7//L-Leucine 61-90-5//Glycine 56-40-6//Zinc Glycinate 7214-08-6//Dl-Phenylalanine 150-30-1//556-50-3 Glycylglycine
Introduction
Product Name | Glycyglycine |
Appearance | White Powder |
CAS | 556-50-3 |
Grade Standard | Medicine grade |
Purity: | 99% |
Function
Glycylglycine is the dipeptide of glycine, making it the simplest peptide.The compound was first synthesized by Emil Fischer and Ernest Fourneau in 1901 by boiling 2,5-diketopiperazine (glycine anhydride) with hydrochloric acid. Shaking with alkali and other synthesis methods have been reported.
Because of its low toxicity, it is useful as a buffer for biological systems with effective ranges between pH 2.5-3.8 and 7.5-8.9, however, it is only moderately stable for storage once dissolved.It is used in the synthesis of more complex peptides.
Glycylglycine has also been reported to be helpful in solubilizing recombinant proteins in E. coli. Using different concentrations of the glycylglycine improvement in protein solubility after cell lysis has been observed.
Application
Specification
Test Items | Standard |
Appearance | White to off-white powder |
HPLC | ≥99% |
Heavy Metals (Pb) | Not more than 10PPM |
Assay | 98.5% to 100.5% |
Chioride(CI) | Not more than0.020% |
Ammonium(NH4) | Not more than 0.02% |
Residue on ignition | Not more than 0.15% |
Sulfate(SO4) | Not more than 0.020% |
Loss on Drying | Not more than 0.20% |
Lron(Fe) | Not less than 30ppm |
Arsenic(As2O3) | Not more than 1ppm |
Other amino acids | Chromatographically not detectable |