China Peptide Powder Argipressine with Best Price 113-79-1, Find details about China Peptide, Peptide Powder from Peptide Powder Argipressine with Best Price 113-79-1
Product Name: Argpressin Acetate
CAS #: 113-79-1
Purity: 98% min.
Molecular Formula: C46H65N15O12S2
Molecular Weight: 1084.23
Argipressin (Arginine vasopressin) is similar to a naturally occuring hormone also known as antidiuretic hormone (ADH) or vasopressin. ADH has two main effects in the body. Firstly, it acts on receptors in the kidney to retain water in the body, which helps to prevent excessive loss of water in the urine. Secondly, ADH causes narrowing of blood vessels (vasoconstriction), thereby limiting blood flow to a particular area of the body. Argipressin is derived from a preprohormone precursor that is synthesized in the hypothalamus, from which it is liberated during transport to the posterior pituitary. Most of it is stored in the posterior part of the pituitary gland to be released into the blood stream; some of it is also released directly into the brain. The vasopressins are peptides consisting of nine amino acids (nonapeptides). The amino acid sequence of arginine vasopressin is Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly, with the cysteine residues forming a sulfur bridge. The structure of oxytocin is very similar to that of the vasopressins: it is also a nonapeptide with a sulfur bridge and its amino acid sequence differs at only two positions.
tems | Standard | Result |
Appearance | White amorphous powder | Conforms |
Solubility | Soluble in water or acetic acid at a concentration of ≥1mg/ml to give a clear, colorless solution | Conforms |
Identity by HPLC | Retention time of the sample must be approximately the same as the retention time of the reference | Conforms |
Amino Acid Composition | ±10% of theoretical except for Cys | Conforms |
Peptide Purity (By HPLC) | ≥95.0% by area integration | 99.3% |
Related Substance (By HPLC) | Total Impurities(%)≤5.0% Largest Single Impurity(%)≤2.0% | 0.7% 0.3% |
Acetate Content (By HPLC) | ≤15.0% | 13.2% |
Water Content (Karl Fischer) | ≤8.0% | 2.0% |
TFA Content (By HPLC) | ≤0.3% | Nd |
Bacterial endotoxin | ≤50 EU/ mg | Conforms |
Residual Solvents (by GC) | EtOH≤5000 ppm MeOH≤3000 ppm DMF≤810 ppm | Nd Nd Nd |
Assay (By HPLC) | 95-105% | 98.2% |
Conclusion | It conforms to Enterprise Standard. |