China Manufacturer Pharmaceutical Intermediate Irbesartan CAS 138402-11-6, Find details about China 138402-11-6, CAS 138402-11-6 from Manufacturer Pharmaceutical Intermediate Irbesartan CAS 138402-11-6
Irbesartan is an angiotensin II (Angiotensin II, Ang II) receptor inhibitor. Angiotensin II receptors are divided into two types: AT1 and AT2. Irbesartan selectively blocks the AT1 receptor of AnglI. It can inhibit the conversion of Ang into Ang, can specifically antagonize the angiotensin-converting enzyme 1 receptor (AT1). The antagonistic effect on AT1 is 8500 times that of AT2. It can selectively block the binding of Ang and AT1 receptor through Chemicalbook. , Inhibit vasoconstriction and the release of aldosterone, resulting in a hypotensive effect. This product does not inhibit angiotensin converting enzyme (ACE), renin, other hormone receptors, nor does it inhibit ion channels related to blood pressure regulation and sodium balance. Irbesartan can also reduce the electrical remodeling of the myocardium, thereby reducing the fatality rate of patients with hypertension. It is currently the most effective drug for the treatment of hypertension and cardiovascular diseases.
Product Name | Irbesartan |
Synonyms | 3-butyl-2-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one;2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'Chemicalbook-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE;IRBESARTAN;BMS-186295;AVAPRO;APROVEL;CS-1097;AVAPRO;SR-47436;BMS-186295 |
MOQ | 1kg |
CAS | 138402-11-6 |
Appearance | white |
Molecular Formula | C25H28N6O |
Molecular Weight | 428.53 |
Assay | >99% |
Application | For research purpose only |
Packing | 25kg/drum |
Storage | Store in a well-closed,light-resistant container |
Remarks | NA |
Custom synthesis | Available |
Product Name | Irbesartan |
Synonyms | 3-butyl-2-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]-2,4-diazaspiro[4.4]non-3-en-1-one;2-BUTYL-3-[[2'-(1H-TETRAZOL-5-YL)[1,1'Chemicalbook-BIPHENYL]-4-YL]METHYL]-1,3-DIAZASPIRO[4.4]NON-1-EN-4-ONE;IRBESARTAN;BMS-186295;AVAPRO;APROVEL;CS-1097;AVAPRO;SR-47436;BMS-186295 |
MOQ | 1kg |
CAS | 138402-11-6 |
Appearance | white |
Molecular Formula | C25H28N6O |
Molecular Weight | 428.53 |
Assay | >99% |
Application | For research purpose only |
Packing | 25kg/drum |
Storage | Store in a well-closed,light-resistant container |
Remarks | NA |
Custom synthesis | Available |
Antihypertensive drugs. Angiotensin -1 (A1)-receptor antagonist. Used to treat high blood pressure.