Pharmaceutical Intermediate Ondansetron HCl 103639 -04-9 Antagonist Antiemetic

China Pharmaceutical Intermediate Ondansetron HCl 103639-04-9 Antagonist Antiemetic, Find details about China Ondansetron Hydrochloride, Ondansetron from Pharmaceutical Intermediate Ondansetron HCl 103639-04-9 Antagonist Antiemetic

Model NO.
103639-04-9
Shelf Life
Two Years
Trademark
Chenxun
Transport Package
25kg / Drum
Specification
25Kg/ drum
Origin
China
HS Code
2942000000
Model NO.
103639-04-9
Shelf Life
Two Years
Trademark
Chenxun
Transport Package
25kg / Drum
Specification
25Kg/ drum
Origin
China
HS Code
2942000000
Pharmaceutical Intermediate Antiemetic Ondansetron HCl 103639-04-9 Antagonist  
 
Basic information
 

Ondansetron hydrochloride
Synonyms: ONDANSETRON Hcl
CAS: 103639-04-9
MF: C18H19N3O· HCl· 2H2O
MW: 365.85
Product Categories: Ondemet, Emeset, Emetron;Other APIs
Usage Antiemetic;Serotonergic receptor antagonist
Biological Activity Selective 5-HT 3 receptor antagonist (K i = 6.16 nM). Antiemetic; prevents emesis induced by cytotoxic drugs and radiation.

Used to treat vomiting caused by chemotherapy, radiotherapy and surgery


Properties

ItemsSpecifications Results
AppearanceWhite or off-white crystalline powderQualified
 
SolubilitySparingly soluble in water and in alcohol,
slightly soluble in isopropyl
 very slightly
Qualified
 
Identification 
 
1.UVMax 209,248,267,310nmQualified
2.IR spectrumConcordant with the working reference.Qualified
3.Discrimination chlorideForward Reaction .Qualified
Water9.0-10.5%9.7%
Residue on Ignition≤0.1%0.02%
Heavy metal≤10ppm<10ppm
Compound D≤0.1%0.04%
Chromatographic purity  
TLC max single impurity≤0.40%0.11%
Other single impurity ≤0.20%0.09%
HPLC Impurity C ≤0.20%0.09%
Imidazole≤0.20%0.02%
2-methylimidazole ≤0.20%0.02%
-Impurity A≤0.20%0.05%
-Other single impurity≤0.10%0.07%
-Total Impurity≤0.50%0.29%
Residual solvent  
Ethanol≤5000ppm240ppm
 
Assay98.0%~102.0%
Calculates on the dried basis.
99.81%
CONCLUSION: CONFORM WITH SPECIFICATION AS PER USP40.

 

Pharmaceutical Intermediate Ondansetron HCl 103639-04-9 Antagonist Antiemetic

Packing

· 1kg/aluminium foil bag, with two plastic bags inside.
· 25kg/fiber drum, with two plastic bags inside.
Size:ID 42cm*H52cm,0.08m3/drum;
Net Weight:25kgs Gross Weight:28kgs.
Pharmaceutical Intermediate Ondansetron HCl 103639-04-9 Antagonist Antiemetic


SHIPPING ADVISE

 By Express
Sultable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to plck up the goods.
 By Air
Sultable for more than 50 kg, Fast: 4-5 days, HIgh cost, alrport to alrportprofesslonal broker needed.
 By sea
Sultable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, protesslonal broker needed.


FAQ

Q1: Can i get small sample?
A: Yes, FREE SAMPLES of some products can be sent on request, but the shipping cost be paid by our customers.
Q2. How to confirm the products quality before placing orders?
A: COA first for you to check the specification,and we test every batch of our product
by HPLC.UV,GC AND TLC AND etc. We also cooperate with independent third party
lab such as SGS,PONY etc.  

Q3: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Money Gram. Also L/C at sight is acceptable for large amount

Why Choose Us
  1. We have 10 years of experience in exporting products, strong market response capabilities and a wide range of trading partners.
  2. We have a variety of certified factories to produce high quality products.
  3. We offer full link hosted services from production to delivery.
  4. We provide testing services prior to shipment of the product.
  5. We will cultivate customers in every country market, let customers develop quickly with us, and win-win cooperation.
  6. Stable supply, delivery on time, quality assurance.