China 99% API Brigatinib Ap26113 CAS 1197958-12-5 for Targeted Cancer Therapy, Find details about China Ap26113, CAS 1197958-12-5 from 99% API Brigatinib Ap26113 CAS 1197958-12-5 for Targeted Cancer Therapy
AP26113
1197958-12-5
Product Name: AP26113
Synonyms: 5-chloro-2-N-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl]-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine;AP26113-ANALOG;(2-((5-Chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)ami;AP26113;AP26113/AP-26113;5-chloro-N2-(4-(4-(diMethylaMino)piperidin-1-yl)-2-Methoxy-5-Methylphenyl)-N4-(2-(diMethylphosphoryl)phenyl)pyriMidine-2,4-diaMine;5-Chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine;5-Chloro-N2-[4-[4-(diMethylaMino)-1-piperidinyl]-2-Methoxyphenyl]-N4-[2-(diMethylphosphinyl)phenyl]
CAS: 1197958-12-5
MF: C27H36ClN6O4P
MW: 575.039301
Boiling point: 737.6±70.0 °C
Density: 1.29±0.1 g/cm3
Description:
AP26113 (also known as Brigatinib) is an investigated small molecule for targeted cancer therapy. It is a potent dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It is mainly under investigation for its treatmentefficacy on non-small cell lung cancer (NSCLC) where ALK is activated and EGFP mutations frequently occur.
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