China 99% Pharmaceutical Intermediate Arimidex Anti-Breast Cancer with Fast and Safe Delivery, Find details about China Arimidex, Arimidex Powder from 99% Pharmaceutical Intermediate Arimidex Anti-Breast Cancer with Fast and Safe Delivery
99% Pharmaceutical Intermediate Arimidex Anti-Breast Cancer with fast and safe delivery
Product information
Arimidex, named ruiting and ruining, are powerful non-steroidal aromatase inhibitors.It can reduce the level of plasma estrogen and inhibit the growth of breast tumors.It was reported that after oral administration of 1mg of this product, the peak time of serum drug concentration was 1.22 + 0.46 hours, the peak time of serum drug concentration was 9.99 + 3.24ng/ml, and the half-life was 35.96 + 14.17 hours.
Certificate of Analysis
Product Name | Arimidex | Other Name | Arimidex Powder |
Purity | 99%min by HPLC | CAS No. |
|
Appearance | white to off white crystalline powder | M.W. | C17H19N5 |
MOQ | 10g | M.F. |
|
Loss on drying | <3.0% | Standard | Factory Standard |
Item | Specification | Result | |
Appearance | white to off white crystalline powder | Complies | |
Related substance (HPLC) | Total impurity ≤0.5% Max single impurity ≤0.1% | 0.2% 0.06% | |
Odor | Characteristic | Complies | |
Assay | 99% | 99.22% | |
Sieve analysis | 100% pass 80 mesh | Complies | |
Heavy Metal | <10ppm | Complies | |
As | <0.1ppm | 0.05ppm | |
Pb | <0.1ppm | 0.05ppm | |
Cd | <0.1ppm | 0.05ppm | |
Residual Solvents | <100ppm | Complies | |
Residual Pesticide | Negative | Complies | |
Total Plate Count | <1000cfu/g | Complies | |
Yeast & Mold | <100cfu/g | Complies | |
E.Coli | Negative | Complies | |
Salmonella | Negative | Complies |
Product Functions
1. For treatment of breast cancer after surgery, as well as for metastasis in both pre and post-menopausal women
2. Arimidex is a potent selective triazole aromatase inhibitor that inhibits the aromatase that cytochrome P-450 is dependent on to prevent the biosynthesis of estrogen. Estrogen is the main stimulating factor for breast cancer cell growth. This drug's half maximal inhibitory concentration (IC50) value to human placental aromatase is 15nmol/L. Compared to the traditional drug steroids, Arimidex can comprehensively and effectively lower the risks of breast cancer recurrence and metastasis, thus extending patients' disease-free survival.
3. Arimidex is suitable for treating postmenopausal advanced breast cancer patients, especially postmenopausal advanced breast cancer patients who experienced recurrence following hormone assisted therapy.
Product Application
1. Anastrazole is used to treat postmenopausal women with estrogen receptor positive breast cancer. This drug is often given in conjunction with other drugs such as sterois in early stage cancers.
2. Anastrazole is taken in tablet form usually just once a day.
3. Medicinal categories: non-steroidal aromatase inhibitors
Indication: Arimidex is used for Postmenopausal women with advanced breast cancer that steroids and other anti-estrogen therapy can not control. For the estrogen receptor-negative patients, can think about the Arimidex if the tamoxifen showed positive clinical response.
4. Pharmacology: Arimidex as a potent, selective nonsteroidal aromatase inhibitors, it can inhibit the postmenopausal patients with adrenal suppression generated intoestrone, significantly reduce plasma estrogen levels. And inhibiting of breast tumor growth. Arimidex significantly affect on adrenal corticosteroids or aldosterone.
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