Donepezil is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the palliative treatment of Alzheimer's disease. Common side effects include gastrointestinal upset. It has an oral bioavailability of 100% and easily crosses the blood-brain barrier. Because it has a biological half-life of about 70 hours, it can be taken once a day.

Functions

Donepezil has been tested in other cognitive disorders including Lewy body dementia and vascular dementia, but it is not currently approved for these indications. Donepezil has been found to improve sleep apnea in Alzheimer's patients. Donepezil has also been studied in patients with Mild Cognitive Impairment, schizophrenia, attention deficit disorder, post-coronary bypass cognitive impairment, cognitive impairment associated with multiple sclerosis, CADASIL, and Down syndrome.

A 3 year NIH trial in patients with mild cognitive impairment reported that donepezil was superior to placebo in delaying rate of progression to dementia during the initial 18 months of the study but this was not sustained at 36 months. In a secondary analysis, a subgroup of individuals with the Apolipoprotein E4 genotype showed sustained benefits with donepezil throughout the study. However at this time donepezil is not indicated for prevention of dementia.

Recent studies suggest that Donepezil can improve speech in children with autism. The studies found that speech of autistic children who were mild to moderately affected appeared to improve from the use of Donepezil.

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Contact us

Xi'an Tian guangyuan Biotech Co.,Ltd.

Tel: 86-29-86333380

Fax: 86-29-86333380

Web:tgybio.en.made-in-china.com



Packing&Shipping

Company information

XIAN Tian Guangyuan Biotech Co.,Ltd.was founded in May 2003, is a professional animal and plant extracts modern and advanced enterprise object, chemical intermediates and active ingredients of natural active throughout the country, plant extracts industry, research and development, production, marketing and other areas have a strong strength. The company is headquartered in the outskirts of Xi'an, under research and development center as well as analysis and testing center, comprehensive strength in the national forefront of the industry. Companies rely on the wisdom and innovation of advanced technology, scientific management and all the staff and a good team spirit, will enable the company to develop a domestic industry with sik-class product quality and international competitiveness of enterprises.

 Our Service

We have more than 500 vendors, we could save your effort to serve customers with supplying all your needs!

1. We has 10 years' exporting experience in active pharmaceutical ingredient products.
    Our professionaland thoughtful after-sales service eliminates your worries.

2.We can provide you with ten thousands of products of different levels.

3. We offer convenient one-station purchasing service.

1> Any inquiries will be replied within 12 hours.
2> Dedication to quality, supply & service.
3> Strictly on selecting raw materials.
4> Reasonable & competitive price, fast lead time.

FAQ

1. Can I buy a sample for evaluation? 

Yes, a small percentage of items are available for single-unit sample purchases online. To make it easier for our customers to locate these items, a separate section in our store will be created soon. For now, if an item offers samples, Click on the link to order the sample.

2. How to make payment? 

We accept payment by telegraphic transfer (T/T) and Western Union .

3. How much does shipping cost? 

Shipping costs vary according to the shipping method and your ship-to country. For your easy reference, the estimated shipping cost you see in your shopping cart is based on courier shipping to the United States. The system will indicate the actual shipping cost based on your selected shipping method 
and ship-to country when you checkout and before you commit to the purchase. Generally, shipping to the UK and other Western European countries is slightly more expensive than to the USA. And shipping to  Asia is slightly less expensive than 
to the USA.

4. Does the shipping cost cover local taxes, import duties, and other import-related costs? 

The shipping cost does not cover any local taxes, import duties, customs clearance, or any other import-related costs levied by your government. The buyer is responsible for these import-related costs. Please check with your local customs office for more information.

5. What shipping options do I have? 

In our continued effort to offer value and flexibility to our customers, we will be offering four different options to deliver your order.

1-200kg Carrier express(DHL/UPS/Fedex/EMS) 

300kg-500kg by air

6. How long is lead time? 

We deliver goods within 3 days for small order, 7-10 days for bulk order.