Dimethomorph fungicides
MF: C21H22CINO4
Dimethomorph CAS No: 110488-70-5
MW: 387.9
MP: 127-148ºC; (E)- isomer 135.7-137.5ºC; (Z)- isomer 169.2-170.2ºC
VP: (E)- isomer 9.7 *10-4 MPa; (Z)- isomer 1.0 *10-3 MPa (both 25ºC)
SG: Bulk density 1318 kg/m3 (20ºC)
Dimethomorph Composition: (E)- to (Z)- ratio is c. 1: 1. Colourless crystals
Dimethomorph Formulation types: 97%TECH 50%WDG, 50%WP
Dimethomorph Solubility.: In water 19 (pH 5), 18 (pH 7), 16 (pH 9) (all in mg/l, 20ºC). In acetone 88 (E), 15 (Z), cyclohexanone 27 (Z), dichloromethane 315 (Z), dimethylformamide 272 (E), 40 (Z), hexane 0.04 (E), 0.02 (Z), methanol 7 (Z), toluene 7 (Z) (all in g/l, 20-23 ºC). In n-hexane 0.11, methanol 39, ethyl acetate 48.3, toluene 49.5, acetone 100, dichloromethane 461 ( all for (EZ), in mg/l).
Dimethomorph Stability: Hydrolytically and thermally stable under normal conditions. Stable for >5 years in the dark. The (E)- and (Z)- isomers are interconverted in sunlight
Toxicological information:
Dimethomorph Oral: Acute oral LD50 for male rats 4300, female rats 3500, male mice >5000, female mice 3700 mg/kg b. W.
Skin and eye: Acute percutaneous LD50 for rats >5000 mg/kg b. W. Not irritant to skin or eyes of rabbits. Not a skin sensitiser (Guinea pigs).
Dimethomorph Purpose: Fungicide effective against Oomycetes, especially Peronosporaceae and Phytophthora spp. (but not Pythium spp. ) in vines, potatoes, tomatoes and other crops. Used in combination with contact fungicides, and applied at 2.0-2.5 kg dimethomorph/ha.