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CE, ISO9001 Approved Matriptase (K21) Polyclonal Antibody

China CE, ISO9001 Approved Matriptase (K21) Polyclonal Antibody, Find details about China St14, Prss14 from CE, ISO9001 Approved Matriptase (K21) Polyclonal Antibody

Model NO.
BS2574
Host
Rabbit
Reactivity
Human, Mouse, Rat
Application_All
Wb: 1:500~1:1000 Ihc/If: 1:50~1:200 IP: 1:10~1:100
Trademark
Bioworld
Transport Package
Refrigerated Transport
Specification
100ug/1mg
Origin
China
HS Code
300219000
Model NO.
BS2574
Host
Rabbit
Reactivity
Human, Mouse, Rat
Application_All
Wb: 1:500~1:1000 Ihc/If: 1:50~1:200 IP: 1:10~1:100
Trademark
Bioworld
Transport Package
Refrigerated Transport
Specification
100ug/1mg
Origin
China
HS Code
300219000
Catalog No.BS2574
Product NameMatriptase (K21) polyclonal antibody
ApplicationsWB IHC IF IP
Alternative NameSuppressor of tumorigenicity 14 protein; Matriptase; Membrane-type serine protease 1; MT-SP1; Prostamin; Serine protease 14; Serine protease TADG-15; Tumor-associated differentially-expressed gene 15 protein; ST14; PRSS14; SNC19; TADG15
Swiss-ProtQ9Y5Y6
HostRabbit
ReactivityHuman,Mouse,Rat
Application_allWB: 1:500~1:1000 IHC/IF: 1:50~1:200 IP: 1:10~1:100
ProductRabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&PurityThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&StabilityStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SpecificityMatriptase (K21) polyclonal antibody detects endogenous levels of Matriptase protein.
BiowMW~ 90 kDa
NoteFor research use only, not for use in diagnostic procedure.
ImmunogenSynthetic peptide, corresponding to the N-terminual of Human Matriptase.

  • Western blot (WB) analysis of Matriptase (K21) pAb at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:CT26 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(40ug) Lane4:PC3 whole cell lysate(40ug)

  • Immunoprecipitation of HEK293T cell lysate using Matriptase (K21) pAb (Sepharose Bead Conjugate) #BD0048(lane 2 and lane 3) .Lane 1 is 30% input. The western blot was probed using Matriptase (K21) #BS2574."↑"(supernatant); "↓(deposition)

Background

Matriptase (also known as MT-SP1, ST14, prostamin and epithin in mouse) is a tumor-associated type II transmembrane serine protease that is highly expressed in many human cancer-derived cell lines and is implicated in extracellular matrix re-modeling, tumor growth, and metastasis. Matriptase performs pleiotropic functions in the development of the epidermis, hair follicles, and cellular immune system. Sphingosine 1-phosphate (S1P, SPP), present in serum-derived lipoproteins, activates matriptase while matriptase activates both urokinase-type plasminogen activator and hepatocyte growth factor (HGF). Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is a Kunitz-type serine protease inhibitor identified as a strong inhibitor of matriptase and HGF.CE, ISO9001 Approved Matriptase (K21) Polyclonal AntibodyCE, ISO9001 Approved Matriptase (K21) Polyclonal Antibody
CE, ISO9001 Approved Matriptase (K21) Polyclonal AntibodyCE, ISO9001 Approved Matriptase (K21) Polyclonal AntibodyCE, ISO9001 Approved Matriptase (K21) Polyclonal Antibody

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