CAS 151767-02-1 High Purity Montelukast Sodium powder
Product Name | CAS 151767-02-1 High Purity Montelukast Sodium powder |
CAS | 151767-02-1 |
Appearance | white powder |
Molecular formula | C35H35ClNNaO3S |
Molecular Weight | 608.17 |
Assay | 98% |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
| What is Montelukast Sodium?Montelukast Sodium is a potent, selective, anti-inflammatory CysLT1 receptor antagonist (IC50 < 5nM) with no appreciable affecton the CysLT2 receptor. In rat colitis Montelukast Sodium has demonstrated the ability to increase PGE2 (Prostaglandin E2 - sc-201225) production and lower COX-2 expression. Inhibition is competitive with respect to leukotrienes - particularly LTD4, a biologically active mediator that plays an important role in the control of several biochemical pathways involving pulmonary and immune system function. |
Function of Montelukast SodiumMontelukastis a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.Montelukast comes as a tablet, a chewable tablet, flash tablet and granules to take by mouth.Montelukast is usually taken once a day with or without food.Montelukast is a CysLT1 antagonist; it blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it. This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation.
Application of Montelukast Sodium
Montelukast is used for a number of conditions including asthma, exercise induced bronchospasm, allergic rhinitis, primary dysmenorrhoea and urticaria. It is mainly used as a complementary therapy in adults in addition to inhaled corticosteroids, if they alone do not bring the desired effect. It is also used to prevent allergic reactions and asthma flare-ups during the administration of intravenous immunoglobulin.
Montelukast is administered as montelukast sodium, with 5.2 mg of montelukast sodium being equivalent to 5 mg of montelukast.
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Packaging & LogisticsPackage:
1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package. 2. Shipping Advise:
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