Product name: Montelukast Sodium
Appearance:White Powder
CAS: 151767-02-1
Molecular weithgs:608.17
Melting point:115°C
Purity:99%
Shelf life:2 years
Storage:Keep in cool dry place..
Specification:Physical&Chemical Control |
ITEM | SPECIFICATION | RESULTS |
Appearance | Fine powder | Complies |
Colorl | White yellow | Complies |
Odor&Taste | Characteristic | Complies |
Assay | ≥99% | 99.53% |
Heavy Metals | ≤10ppm | Complies |
Pb | ≤2ppm | Complies |
As | ≤2ppm | Complies |
Hg | ≤1ppm | Complies |
Cadmium | ≤1ppm | Complies |
Sulphates | ≤300ppm | Complies |
Ammonium | ≤200ppm | Complies |
Iron | ≤10ppm | Complies |
Microbiological Control |
Total plate count | ≤1000CFU/G | Complies |
Yeast & mold | ≤100 CFU /G | Complies |
Total coli forms | ≤100 CFU /G | Complies |
E.coli | Negative | Negative |
Salmonella | Negative | Negative |
Product description:Montelukast Sodium is a potent, selective, anti-inflammatory CysLT1 receptor antagonist (IC50 < 5nM) with no appreciable affecton the CysLT2 receptor. In rat colitis Montelukast Sodium has demonstrated the ability to increase PGE2 (Prostaglandin E2 - sc-201225) production and lower COX-2 expression. Inhibition is competitive with respect to leukotrienes - particularly LTD4, a biologically active mediator that plays an important role in the control of several biochemical pathways involving pulmonary and immune system function.
Function & Application:
Function of Montelukast Sodium
Montelukastis a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.Montelukast comes as a tablet, a chewable tablet, flash tablet and granules to take by mouth.Montelukast is usually taken once a day with or without food.Montelukast is a CysLT1 antagonist; it blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it. This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation.
Application of Montelukast Sodium
Montelukast is used for a number of conditions including asthma, exercise induced bronchospasm, allergic rhinitis, primary dysmenorrhoea and urticaria. It is mainly used as a complementary therapy in adults in addition to inhaled corticosteroids, if they alone do not bring the desired effect. It is also used to prevent allergic reactions and asthma flare-ups during the administration of intravenous immunoglobulin.
Montelukast is administered as montelukast sodium, with 5.2 mg of montelukast sodium being equivalent to 5 mg of montelukast.
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Company Profile
Xi'an Wucine Bio Industries Inc is a national key high-tech enterprise,which mainly specializes in the R&D,operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access.Our company has independent R&D center,raw material synthesis workshop,has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
FAQ
1.Are you a manufacturer or trade company?
We are a professional manufacturer.
2.What's your payment terms?
Standard terms: T/T in advance and Western Union.
Also L/C at sight is acceptable for large amount. 3.What's your shipping time?
We have a large stock, which means we can deliver the goods to you immediately.
4.How do you ensure the quality of your products?
Strict QC with 6 steps testing from raw material purchase to finished product.
5.How do you ship the order normally?
For large qty order,ship the goods by sea.
For small qty order, by air or express. We supply optional express for you, including DHL,FEDEX,UPS,TXT,EMS,and so on.
6.What's your loading port?
Usually Shanghai, Qingdao, Tianjin, Guangzhou.