Top Quality and Competitive Price Simvastatin CAS No. 79902 -63-9
China Top Quality and Competitive Price Simvastatin CAS No. 79902-63-9, Find details about China Simvastatin, Simvastatin Powder from Top Quality and Competitive Price Simvastatin CAS No. 79902-63-9
Top Quality and Competitive Price Simvastatin CAS No. 79902-63-9
| Product Name | Simvastatin |
| CAS | 79902-63-9 |
| MF | C25H38O5 |
| MW | 418.57 |
| Density | 1.11±0.1 g/cm3(Predicted) |
| Appearance | White crystalline powder |
| Assay | 98%min |
Simvastatin is a lipid-lowering agent derived synthetically from a fermentation product of the fungus Aspergillus terreus. Hydrolyzed in vivo to an active metabolite, simvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis. This agent lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing MHC II (major histocompatibility complex II) on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells.
Items | Specifications | Results |
Appearance | White or almost white, crystalline powder | White crystalline powder |
Specific rotation | Meet the requirement | Complies |
IR | IR spectrum of sample conforms to that of the reference standard | Complies |
Appearance of solution | The solution is clear and not more intensely colored than reference solution BY7 | Complies |
Specific optical rotation | +285o~+300o | +288.4o |
Sum of impurities E and F | Not more than 1.0% | 0.26% |
Sum of Impurities B and C | Not more than 0.8% | 0.18% |
Impurity A | Not more than 0.4% | 0.03% |
Impurity D | Not more than 0.4% | 0.17% |
Impurity G | Not more than 0.4% | 0.13% |
Unspecified impurity | Not more than 0.10% | 0.08% |
Sum of impurities (other than E and F ) | Not more than 1.0% | 0.72% |
Heavy mentals | Not more than 20ppm | Less than 20ppm |
Loss on drying | Not more than 0.5% | 0.08% |
Sulfated ash | Not more than 0.1% | 0.03% |
Ethanol | Not more than 5000ppm | 588ppm |
Assay (on the dried basis ) | 97.0% to 102.0% of C25H38 O5 | 100.10% |
Conclusion | The results conform with the specifications | |
Simvastatin can be used to lower elevated total cholesterol.
Simvastatin reduces the risk of death from coronary heart disease and non-fatal myocardial infarction.
Simvastatin reduces the risk of stroke and transient ischemic attack.
Simvastatin delays the progression of atherosclerosis
Xi'an Wucine Bio Industries Inc is a national key high-tech enterprise,which mainly specializes in the R&D,operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access.Our company has independent R&D center,raw material synthesis workshop,has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
1.Are you a manufacturer or trade company?
We are a professional manufacturer.
2.What's our payment terms?
Standard terms: T/T in advance and Western Union. Also L/C at sight is acceptable for large amount.
3. What's your shipping time?
We have a large stock, which means we can deliver the goods to you immediately.
4.How do you ensure the quality of your products?
Strict QC with 6 steps testing from raw material purchase to finished product.
5.How do you ship the order normally?
For large qty order,ship the goods by sea. For small qty order, by air or express. We supply optional express for you, including DHL,FEDEX,UPS,TXT,EMS,and so on.
6.What's your loading port?
Usually Shanghai, Qingdao, Tianjin, Guangzhou
You Might Also Like
Zinc It Done Water-Based Galvanizing Spray Paint Aqueous Gal......
EPA/Carb Certificated Fuel Line Fuel Hose for Garden Machine......
100g high performance desiccant in Tyvek
Truck Spare Parts Weichai Engine Intake Rocker Arm Best
Art Glass Smoking Water Pipe ( AY 020)
Pdadmac 40% Cationic Polymer for Sludge Dewatering
Hot-Sale HDI Multilayer Printed Circuit Board Fr4 PCB Power ......
High-End Wall Mounted Storage Holder Rack for Kitchen Goldmi......
Rth -1100A Non Woven Sheet Cutting Machine Sheet Label Cutti......
Non Crosslinked Hyaluronic Acid Meso Filler for Lip Injectio......