Simvastatin CAS NO.79902-63-9 C25H38O5 Cardiovascular

       

Quick Details 

Name	Simvastatin
CAS NO.	79902-63-9
Molecular Formula	C25H38O5
Molecular Weight	418.57
Melting Point	139 °C
EINECS	404-520-2
Appearance	White Crystalline powder
Purity	99% Min

  

Simvastatin  is a hypolipidemic drug used with exercise, diet, and weight-loss to control elevated cholesterol, or hypercholesterolemia.

It is a member of the statin class of pharmaceuticals. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. 

 

Certification  

 

Appearance	White or almost white, crystalline powder	White crystalline powder
Specific rotation	Meet the requirement	Complies
IR	IR spectrum of sample conforms to that of the reference standard	Complies
Appearance of solution	The solution is clear and not more intensely colored than reference solution BY7	Complies
Specific optical rotation	+285o~+300o	+288.4o
Sum of impurities E and F	Not more than 1.0%	0.26%
Sum of Impurities B and C	Not more than 0.8%	0.18%
Impurity A	Not more than 0.4%	0.03%
Impurity D	Not more than 0.4%	0.17%
Impurity G	Not more than 0.4%	0.13%
Unspecified impurity	Not more than 0.10%	0.08%
Sum of impurities (other than E and F )	Not more than 1.0%	0.72%
Heavy mentals	Not more than 20ppm	Less than 20ppm
Loss on drying	Not more than 0.5%	0.08%
Sulfated ash	Not more than 0.1%	0.03%
Ethanol	Not more than 5000ppm	588ppm
Assay (on the dried basis )	97.0% to 102.0% of C25H38 O5	100.10%
Conclusion	The results conform with the specifications

   

Functions

 

Simvastatin (INN) is a hypolipidemic drug used with exercise, diet, and weight-loss to control elevated

cholesterol, or hypercholesterolemia. It is a member of the statin class of pharmaceuticals.

(1) The primary uses of simvastatin are for the treatment of dyslipidemia and the prevention of cardiovascular

disease.

(2) It also can used for the patient with coronary heart disease.

Packing:







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Simvastatin CAS NO.79902-63-9 C25H38O5 Cardiovascular