Antidiabetic Apis Pharmaceutical Alogliptin Benzoate CAS No. 850649-62-6
China Antidiabetic Apis Pharmaceutical Alogliptin Benzoate CAS No. 850649-62-6, Find details about China Alogliptin Benzoate, Pharma Grade from Antidiabetic Apis Pharmaceutical Alogliptin Benzoate CAS No. 850649-62-6
Basic Info.
Model NO.
CAS NO. 850649-62-6
Appearance
White, Crystalline Powder
Transport Package
25kg/Drum
Origin
China
Model NO.
CAS NO. 850649-62-6
Appearance
White, Crystalline Powder
Transport Package
25kg/Drum
Origin
China
Product Desciption
Antidiabetic APIs Pharmaceutical Alogliptin Benzoate CAS NO. 850649-62-6
Basic Information:
1) Name:Alogliptin benzoate
2) Purity: 99%
3) Cas no.:850649-62-6
4) Appearance: White Powder
5) Supply Ability : 2Mt/Per Month
6) Storage: Store in a well-closed container away from moisture
Incretin is a peptide hormone produced by gastrointestinal tract after meal, which can promote the secretion of insuliin by islet β cells. It includes glucagon like peptide-1 (GLP-1) and Glucose dependent insuliinotropic peptide (GIP), which are secreted by L cells in ileum and colon and K cells in duodenum respectively. GLP-1 and GIP, as active hormones, can be released into the blood circulation within a few minutes after ingestion of food, but they will be quickly inactivated by serine protease DPP-4. The level of postprandial incretin in patients with type 2 diabetes mellitus is significantly lower, so preventing the inactivation of incretin to increase its action time will effectively reduce blood glucose. As a DPP-4 inhibitor, agliptin benzoate can reduce the inactivation of GLP-1 in vivo by selectively inhibiting DPP-4, increase the level of GLP-1 in vivo, and reduce blood glucose. When the blood glucose is reduced to the normal level, it will not continue to play a hypoglycemic role, so it can effectively reduce the risk of hypoglycemia. In addition, DPP-4 inhibitors can delay gastric emptying, increase satiety, inhibit appetite, and help patients reduce body weight. Therefore, these drugs can effectively reduce blood glucose, but also reduce the risk of hypoglycemia and increased body weight, overcome the obstacles of patients' treatment, and bring new hope to the treatment of diabetes.
Basic Information:
1) Name:Alogliptin benzoate
2) Purity: 99%
3) Cas no.:850649-62-6
4) Appearance: White Powder
5) Supply Ability : 2Mt/Per Month
6) Storage: Store in a well-closed container away from moisture
Incretin is a peptide hormone produced by gastrointestinal tract after meal, which can promote the secretion of insuliin by islet β cells. It includes glucagon like peptide-1 (GLP-1) and Glucose dependent insuliinotropic peptide (GIP), which are secreted by L cells in ileum and colon and K cells in duodenum respectively. GLP-1 and GIP, as active hormones, can be released into the blood circulation within a few minutes after ingestion of food, but they will be quickly inactivated by serine protease DPP-4. The level of postprandial incretin in patients with type 2 diabetes mellitus is significantly lower, so preventing the inactivation of incretin to increase its action time will effectively reduce blood glucose. As a DPP-4 inhibitor, agliptin benzoate can reduce the inactivation of GLP-1 in vivo by selectively inhibiting DPP-4, increase the level of GLP-1 in vivo, and reduce blood glucose. When the blood glucose is reduced to the normal level, it will not continue to play a hypoglycemic role, so it can effectively reduce the risk of hypoglycemia. In addition, DPP-4 inhibitors can delay gastric emptying, increase satiety, inhibit appetite, and help patients reduce body weight. Therefore, these drugs can effectively reduce blood glucose, but also reduce the risk of hypoglycemia and increased body weight, overcome the obstacles of patients' treatment, and bring new hope to the treatment of diabetes.
Pic
You Might Also Like
Zinc It Done Water-Based Galvanizing Spray Paint Aqueous Gal......
EPA/Carb Certificated Fuel Line Fuel Hose for Garden Machine......
100g high performance desiccant in Tyvek
Truck Spare Parts Weichai Engine Intake Rocker Arm Best
Art Glass Smoking Water Pipe ( AY 020)
Pdadmac 40% Cationic Polymer for Sludge Dewatering
Hot-Sale HDI Multilayer Printed Circuit Board Fr4 PCB Power ......
High-End Wall Mounted Storage Holder Rack for Kitchen Goldmi......
Rth -1100A Non Woven Sheet Cutting Machine Sheet Label Cutti......
Non Crosslinked Hyaluronic Acid Meso Filler for Lip Injectio......