China GMP Standard Manufacturer Supply 99% Medicine Peptide Ace′ -031 / Ace 031 Powder CAS: 616204-22-9, Find details about China Ace 031, Ace′-031 from China GMP Standard Manufacturer Supply 99% Medicine Peptide Ace′ -031 / Ace 031 Powder CAS: 616204-22-9
Product Name: | ACE 031 |
Synonyms: | ACE 031 (untagged), ACVR2B |
CAS: | 616204-22-9 |
MF: | C10H17N3O6S |
MW: | 1311.45 |
EINECS: | ----- |
Product Categories: | Amino Acid Derivatives;Peptide |
Purity: | 99% |
ACE 031 is a protein therapeutic. Muscle growth is regulated by proteins in the body which act as on or off switches. The drug contains a recombinant fusion protein which is produced by joining a portion of the human ActRIIB receptor to a portion of human antibody.
The muscles may become stronger when the drug acts by reducing the off signal which stops muscle production. The drug builds up the muscle and increases its strength by inhibiting a decoy receptor that binds myostatin before it is able to bind with active type II receptor (ActRIIB).
1. Treatment of hypertension: ACE inhibitors are the first choice for patients with hypertension associated with heart failure or diabetes mellitus or nephropathy.
2. the treatment of congestive heart failure and myocardial infarction: can reduce the death rate of heart failure, improve the prognosis of congestive heart failure, prolong life.It can reduce the mortality rate of myocardial infarction complicated with heart failure and improve hemodynamics and organ perfusion.
3. the treatment of diabetic nephropathy and other nephropathy: insuli dependent and insuli independent diabetes, whether or not hypertension can improve or prevent the deterioration of renal function.
Item | Specification | Result |
Appearance | White powder | Complies |
Identification | Positive | Complies |
Assay | 99.0% min | 99. 3% |
Loss on Drying | 6.0%max. | 4.80% |
Mass Balance | 95.0~105.0% | Complies |
Acetate Content (HPIC) | 12.0%max. | 10.80% |
Peptide Content (N%) | 80.0%min. | 88.00% |
Amino Acid Composition | ±10% of theoretical | Complies |
Single Impurity (HPLC) | 1.0%max. | 0.85% |