Chinese name: Atazanavir

English name: Atazanavir

English alias: Atazanavir [INN:BAN]; BMS 232632; ATV; BMS-232632; CGP 73547; HSDB 7339; Latazanavir; Reyataz; UNII-QZU4H47A3S;

CAS:198904-31-3

Molecular formula: C38H52N6O7

Molecular weight: 704.8555

Atazanavir is a novel aza-type peptide inhibitor (PI) that exhibits in vitro activity distinct from non-peptide PI such as Nelfinavir and is based on X-ray diffraction of the enzyme-aza-peptide complex Research and design, with C-2 symmetry of the chemical structure. It is a highly selective and potent inhibitor of HIV-1 protease and inhibits viral structural proteins, reverse transcriptase, integrase and protease production by blocking the cleavage of viral gap and gap-pol precursor polyproteins, HIV-1 infected cells release non-infectious, immature virus particles