Tianeptine has strong antidepressant and anxiolytic properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in elderly patients and in those following alcohol withdrawal; such patients can be more sensitive to the adverse effects of psychotropic drugs. Recent interesting results indicate anticonvulsant and analgesic activity of tianeptine and its possible interaction with adenosine A1 receptors.

Tianeptine is neuroprotective via multiple neurochemical and cellular mechanisms. In theory, tianeptine's neuroprotective action makes it a potential life-extension drug. When an organism is under stress, or perceives itself under stress, the hypothalamus secretes corticotropin-releasing hormone/factor (CRH/CRF). CRH/CRF in turn increases secretion of adrenocorticotrophic hormone (ACTH) from the anterior pituitary. ACTH in turn stimulates the release of glucocorticoids from the adrenal cortex. Persistent, uncontrolled physical and psychosocial stress causes excess cortisol secretion from the adrenal glands. Excess cortisol causes dendritic shrinkage in the hippocampus and a contrasting growth of dendrites in the lateral amygdala. These stress-induced changes tend to lower mood; they can cause clinical depression in the genetically vulnerable. Current evidence suggests that tianeptine acts to prevent and even reverse stress-induced neural damage, promoting both neuronal survival and synaptic plasticity. 

Zangu is a professional company focusing on the development of medical and beauty products. Our products is mainly of a series of dermal fillers that are used to treat signs of aging.The gel is clear, colorless and biodegradable.The products are developed to smooth outlines and wrinkles, shape facial contours and add volume to lips. It is very safe and effective to treat the entire face creating a more beautiful and youthful look.

1. who are we?
We are based in Henan, China, start from 2021,sell to North America(25.00%),Eastern Europe(15.00%),Mid East(15.00%),South America(10.00%),Eastern Asia(10.00%),Western Europe(10.00%),Central America(5.00%),Southeast Asia(3.00%),Africa(2.00%),Northern Europe(2.00%),Southern Europe(2.00%),Oceania(1.00%). There are total about 51-100 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Sculptra,PDO Thread,Micro Cannula

4. why should you buy from us not from other suppliers?
PDO Thread,Micro Cannula,Sculptra,Liporase

5. what services can we provide?
Accepted Delivery Terms: FOB,CFR,CIF,EXW,FAS,CIP,FCA,CPT,DEQ,DDP,DDU,Express Delivery,DAF,DES;
Accepted Payment Currency:USD,EUR,JPY,CAD,AUD,HKD,GBP,CNY,CHF;
Accepted Payment Type: T/T,L/C,D/P D/A,MoneyGram,Credit Card,PayPal,Western Union,Cash,Escrow;
Language Spoken:English,Chinese,Spanish,Japanese,Portuguese,German,French,Russian,Korean,Hindi,Italian