Pyrroloquinoline quinone (PQQ) a novel vitamin-like compound found in plant foods which is showing a wide range of benefits to brain and body function based upon preclinical studies and initial clinical evaluation.Although PQQ is not currently viewed as a vitamin, it is likely to be considered an essential nutrient in the future.

Pyrroloquinoline quinone disodium salt (PQQ-2Na) is a sodium salt derivative of pyrroloquinoline quinone (PQQ). Pyrroloquinoline quinone disodium salt is the active ingredient of currently marketed health products. Pyrroloquinoline quinone disodium salt has nerve growth factor-inducing activity and is resistant to Parkinson's disease. Pyrroloquinoline quinone disodium salt has a certain effect and can prevent immune liver damage.

PQQ is pyrroloquinoline quinone, which is a new prosthetic group that can treat heart disease, neurological diseases, protect the liver, and maintain mitochondrial function. Pyrroloquinoline quinone widely exists in prokaryotes, plants and mammals. It is not only the prosthetic group of many enzymes, but also the function of transferring electrons, protons and chemical groups in enzymatic reactions, and can also stimulate microorganisms. The growth of plants, the germination of plant pollen, promote the growth of plants.

1.Pyrroloquinoline quinone disodium salt reverses cognitive impairment caused by chronic oxidative stress and improve performance on memory tests in animal models.
2.Pyrroloquinoline quinone disodium salt supplementation stimulates the production and release of nerve growth factor.
3.Pyrroloquinoline quinone disodium salt protects against the self-oxidation of the DJ-1 gene, an early step in the onset of Parkinson's disease.
4.Pyrroloquinoline quinone disodium salt protects brain cells against oxidative damage in models of strokes.
5.Pyrroloquinoline quinone disodium salt blocks the formation of inducible synthase (iNOS), a major source of reactive nitrogen species (RNS) that are so damaging to brain cells.
6.Pyrroloquinoline quinone disodium salt protects against the likelihood of severe stroke in an experimental animal model for stroke.
7.Pyrroloquinoline quinone disodium salt protects the brain against neurotoxicity induced by other powerful toxins, including mercury, glutamate, and oxidopamine (a potent neurotoxin used by scientists to induce 8.Parkinsonism in laboratory animals).
9.Pyrroloquinoline quinone disodium salt prevents development of alpha-synuclein, a protein associated with Parkinson's disease.
10.Pyrroloquinoline quinone disodium salt also protects nerve cells from the damaging effects of the beta-amyloid-protein linked with Alzheimer's disease.

Pyrroloquinoline quinone disodium salt may have the power to help protect brain function well into our advanced years. Initial evidence of this was demonstrated in a 2009 study published in the medical journal Food Style. In this double-blind, placebo-controlled study, 71 men and women aged 45-65 consumed foods fortified with 20 mg of PQQ (as found in our new maximum potency formula), Pyrroloquinoline Quinone plus CoQ10, or placebo, for 12 weeks. Throughout the study, subjects participated in cognitive tests designed to measure memory, recall and cerebral function. The graph shown illustrates the results. Similar results were reported in a 2011 follow-up study in which Pyrroloquinoline Quinone was given directly as a supplement.