China Cardiac Care Pimobendan Powder 74150-27-9 Veterinary Pimobendan, Find details about China Pimobendan Powder, Purity Pimobendan from Cardiac Care Pimobendan Powder 74150-27-9 Veterinary Pimobendan
Product Name | Pimobendan |
CAS | 74150-27-9 |
Appearance | White crystalline powder |
MF | C19H18N4O2 |
Molecular Weight | 334.37 |
Purity | 99% min |
Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder |
Shelf Life | 24 Months |
Item | Specifications | Results |
Appearance | White crystalline Powder | Confirms |
solubility | Practically insoluble in water, freely soluble in dimethylformamide, slightly soluble in aceton and in methano. | Conforms |
Identification | Infrared absorption spectrophotometry , Comparison pimobendan CRS | Conforms |
Heavy metals | ≤10ppm | 1ppm |
Water | ≤1.0% | 0. 1% |
Assay (HPLC) | 98.0%~100.0% | 99.83% |
Sulphated ash | ≤0.1% | 0.01% |
Related substances(HPLC) | Impurity A:≤0.1% | 0.03% |
Impurity B:≤0.1% | 0.07% | |
Any other impurity:≤0.1% | 0.05% | |
Total impurity:≤0.2% | 0.17% | |
Conclusion | The results conforms with Enterprise standards |
Function and Application
Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction
Pimobendan is mainly used in the management of heart failure in dogs, most commonly caused by myxomatous mitral valve desease (also previously known as endocardiosis), ordilated cardiomyopathy.
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