Essential hypertension.

PHARMACOKINETICS
According to foreign clinical studies data, valsartan was rapidly absorbed after oral administration and the absolute bioavailability was 25%. A 46% decrease in the absorption rate was observed when the drug was taken after meals but no significant decrease of clinical effects was observed, so the drug can be taken without regard to meals. Its peak plasma concentration is attained within 2 to 3 hours and its elimination half-life is 6 to 7 hours, the binding of valsartan to human plasma proteins ranged from 94% to 97%. Take valsartan once daily, valsartan plasma concentration reaches to steady state three days later. Valsartan is metabolized as unchanged drug, mainly excreted (about 70%) by biliary tracts, and others is excreted by the kidney.

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Company Profile

1)Lunan Pharmeceutical Group is a large and comprehensive pharmacutical enterprise, a major national innovative enterpre and States Key High New Technology Enterprise that produces, researches and sells traditional Chinese medicine, chemical medicine and biological medicine.

2)The group is comprised of seven subsidiary companies including Lunan Hope Pharmaceutical Co., Ltd., Lunan Better Pharmaceutical Co., Ltd., Shandong New Time Pharmaceutical Co., Ltd., Lunan New Time Medical Co., Ltd. etc...It is one of the top 500enterprises of China, and it has been the top 100 taxpayer for 8 years in Shandong province. 

Our Advantages

Our group is equipped with high R&D Platforms, such as National Chiral Pharmaceutical Engineering Technology Research Center, National Mammalian Cells Efficiently Express Engineering Laboratory, State Key Laboratory of Generic Marufacture Technology of TcM, National Enterprise Techecogy center, Postdoctoral Programme andTaishan Scholars Position.

The group built up a long technology partnership with more than 100 institutes and universities at home and abroad meanwhile it enhances its own independent innovation system. Lunan Enterprise Technology center's technology innovative ability ranks the forefront in Pharmaceutical industry and got the title"Top Ten Best Industrial Enterprises of Domestic Pharmaceutical R & D Product Line".