China High Quality Ciprofloxacin HCl with CAS 86393-32-0, Find details about China Ciprofloxacin HCl, 86393-32-0 from High Quality Ciprofloxacin HCl with CAS 86393-32-0
Information:
Name: | Ciprofloxacin Hydrochloride/ Ciprofloxacin hcl |
CAS NO.: | 86393-32-0 |
Molecular Formula: | C17H18FN3O3HCL |
Molecular Weight : | 385.81 |
Chemical Name : | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic |
Specification:
Item | Standard(USP35) | Test Result |
Description | White or off-white crystalline powder | Conform |
Solubility | Meets the requirement | Conform |
Colour of solution | Meets the requirement | Conform |
Fluoroquinoloic Acid | ≤0.2% | <0.2% |
Sulfate | ≤0.04% | <0.04% |
PH | 3.0~4.5 | 3.7 |
Water | 4.7~6.7% | 6.20% |
Residue on Ignition | ≤0.1% | 0.02% |
Heavy metals | ≤0.002% | <0.002% |
Chromatographic Purity | Meets the requirement | Conform |
Single impurity | ≤0.2% | 0.11% |
Any other individual impurities | ≤0.2% | <0.2% |
Total impurities | ≤0.5% | 0.38% |
Assay | 98.0~102.0% | 99.40% |
Using:
Used for urinary reproductive system caused by sensitive bacteria infections, respiratory infections, gastrointestinal infections,
typhoid fever, bone and joint infection, skin soft tissue infection, sepsis systemic infection, etc.
Function:
USE: pharmaceutical raw material
Ciprofloxacin HCl drug is used for the treatment of Bacterial infection of Respiratory tract, UTI, Uncomplicated Cystitis in females, GI, Chronic Bacterial Prostatitis, CNS, Immuno compromised patients, Skin, Bone and Joint Infections, Uncomplicated cervical and urethral gonorrhea.
Ciprofloxacin HCl drug has in vitro activity against a wide range of gram-negative and gram-positive organisms.
Ciprofloxacin HCl drug inhibits bacterial DNA gyrase, an enzyme responsible for counteracting excessive supercoiling of DNA during replication or transcription. The mechanism of action of quinolones, including
Ciprofloxacin HCl drug, is different from that of other antimicrobial agents such as beta-lactams, macrolides, tetracyclines, or aminoglycosides; therefore, organisms resistant to these drugs may be susceptible to Ciprofloxacin HCl drug. There is no known cross-resistance between ciprofloxacin HCl drug and other classes of antimicrobials.
Items of analysis | Specification | Results |
Appearance | Colorless to pale yellow crystalline powder | light yellow crystalline powder |
Fluoroquinolone acid | ≤0.2% | <0.2% |
Sulfate | ≤0.04% | <0.04% |
PH(1 in 40) | 3.0~4.5 | 3.6 |
Water by K.F. | 4.7~6.7% | 6.1% |
Residue on ignition | ≤0.1% | 0.02% |
Heavy metals | ≤0.002% | <0.002% |
Chromatographic purity | Meets the requirements | conforms |
Single impurity | ≤0.2% | 0.11% |
Total impurity | ≤0.5% | 0.36% |
Assay | 98.0~102.0% | 99.5% |
Conclusion | Qualified |
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