Introduction
 

Taxol/ Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'TAXOL'. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent. A newer formulation, in which paclitaxel is bound to albumin, is sold under the trademark Abraxane.

Function

 

Taxol/  Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is also used for the prevention of restenosis. Paclitaxel stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division. Together with docetaxel, it forms the drug category of the taxanes .

Application

(1). As drugs raw materials of anti-cancer , it is mainly used in pharmaceutical field;
(2). As active ingredients of products for preventing breast cancer, ovarian cancer and lung cancer, it is mainly used in health product industry.

ITEM	SPECIFICATION	RESULTS
Appearance	Fine powder	Complies
Colorl	White	Complies
Odor&Taste	Characteristic	Complies
Assay	≥99%	99.53%
Heavy Metals	≤10ppm	Complies
Pb	≤2ppm	Complies
As	≤2ppm	Complies
Hg	≤1ppm	Complies
Cadmium	≤1ppm	Complies
Sulphates	≤300ppm	Complies
Ammonium	≤200ppm	Complies
Iron	≤10ppm	Complies
Microbiological Control
Total plate count	≤1000CFU/G	Complies
Yeast & mold	≤100 CFU /G	Complies
Total coli forms	≤100 CFU /G	Complies
E.coli	Negative	Negative
Salmonella	Negative	Negative

 

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Xi'an Reliable Bio-Engineering Co., Ltd as a high-tech enterprise which focusing on sales and service of biomedical and large health field, Our main products are widely used in health care products, cosmetics & Pharmaceutical industry, and in functional foods and beverages,etc.Beside some advanced extraction, separation, purification and drying equipments, our factory was also equipped with imported quality testing equipments, such as HPLC, GC, AFS, UV, etc. For production we have professional production technicians to implement scientific production flow supervision and quality inspections, all those can ensure the safety, efficacy and stability of our products. After years developing we have cooperated and got many many good feedbacks from customers around the world.Integrity, innovation, mutual benefit and common prosperity, sustainable business is our pursuit, we will always trying our best to supply quality assured competitive goods with best service to all customers from worldwide.