China Anti Peptic Ulcer Drugs 99.5% Cimetidine CAS 51481-61-9 with Factory Bulk Price, Find details about China Cimetidine, 51481-61-9 from Anti Peptic Ulcer Drugs 99.5% Cimetidine CAS 51481-61-9 with Factory Bulk Price
Quick detail:
Name: Cimetidine
CAS No.: 51481-61-9
Formula: C10H16N6S
Molecular Weight: 252.38
EINECS: 257-232-2
Density: 1.27 g/cm3
Melting Point: 139-144 ° C
Boiling Point: 488 ° C at 760 mmHg
Flash Point: 248.9 ° C
Solubility: 0.5 g/100 mL at 20 ° C in water
Appearance: White solid
Usage: For the treatment of peptic ulcer
Description:
1. Cimetidine, sold under the brand name Tagamet among others, is ahistamine H2 receptor antagonist that inhibits stomach acidproduction. It is available over-the-counter and is mainly used in the treatment of heartburn and peptic ulcers.
2. The development of longer-acting H2 receptor antagonists with fewer drug interactions and adverse effects, such as ranitidine and famotidine, decreased the use of cimetidine, and though it is still used, cimetidine is no longer among the more widely used of the H2-receptor antagonists.
Application:
1. Cimetidine is used to treat ulcers of the stomach and intestines and prevent them from coming back after they have healed.
(1) Treats stomach and intestinal ulcers;
(2) Helps prevent ulcers from forming;
(3) Treats some hypersecretory conditions;
(4) Decreases stomach acid production.
2. This medication is also used to treat certain stomach and throat (esophagus) problems caused by too much stomach acid (e.g., Zollinger-Ellison syndrome, erosive esophagitis) or a backward flow of stomach acid into the esophagus (acid reflux disease/GERD). Decreasing extra stomach acid can help relieve symptoms such as stomach pain, heartburn, difficulty swallowing, persistent cough, and trouble sleeping. It can also prevent serious acid damage to your digestive system (e.g., ulcers, cancer of the esophagus).
3. Cimetidine belongs to a class of drugs commonly called H2 blockers. It works by reducing the amount of acid in your stomach.
4. This medication is also available without a prescription. It is used to treat occasionalheartburn caused by too much acid in the stomach (also called acid indigestion or sour stomach). It is also used to prevent heartburn and acid indigestion caused by certain foods and beverages. If you are taking this medication for self-treatment, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist. (See also Precautions.)
COA:
ITEM | STANDARD | RESULT |
IDENTIFICATION | POSITIVE | POSITIVE |
MELTING POINT | 140-144ºC | 140-143ºC |
LOSS ON DRYING | ≤0.5% | 0.05% |
SULFATE ASH | ≤0.1% | 0.03% |
ASSAY | ≥99.0% | 99.85% |
CHROMATOGRAM PURITY | COMPLIES | |
TOTAL IMPURITY | ≤0.2% | COMPLIES |
HEAVY METAL | ≤20PPM | COMPLIES |
CONCLUSION | COMPLIED TO THE STADARD OF USP25 |
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