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Product name: Setipiprant  

CAS NO: 866460-33-5

Purity:99%

MF :C24H19FN2O3

Grade: Pharma Grade 

What is Setipiprant?

Setipipran is an oral drug that's currently being tested for use as a hair loss treatment. It was initially developed as a treatment for allergic rhinitis, but recent hair loss-related discoveries have made it a better candidate for hair loss reversal.

How Does It Work?

In short, setipiprant is an antagonist of the prostaglandin D2 receptor 2 (DP2). This receptor is responsible for bonding with and responding to certain prostaglandins, particularly PGD2. This prostaglandin has been linked to various pathological responses, including those linked to allergies, asthma, and inflammation.
 

For Allergies/Asthma

As setipiprant is believed to interfere with the receptors known to contribute to allergies/allergic responses, the drug was first tested on allergies and asthma.

In clinical trials, the drug performed quite well in the treatment of allergen-induced airway responses in asthmatic patients. It was also well tolerated by participants. However, its results were similar to those of drugs already on the market, so further trials were discontinued.

 

For Hair Loss

In 2012, researchers discovered a link between the PGD2 receptor and hair loss. More specifically, this receptor is seen at high levels in the scalps of men diagnosed with Androgenetic Alopecia (AGA).

AGA (Male-Pattern Baldness) is the most common cause of hair loss in men, though it's also seen in women (Female Pattern Hair Loss). It's believed to be caused by a sensitivity to DHT, which is an androgen hormone that attaches to the follicles and leads to inflammation and irritation.



 

It's known that PGD2 is produced from PGD2 synthase, an enzyme. And PGD2 synthase levels are increased by - you guessed it! - DHT. With an increase in PGD2, the PGD2 receptor on the scalp is then triggered, which causes inflammation.

According to researchers, setipiprant steps in before PGD2 attaches to the receptors, and therefore prevents receptor activation and, as a result, hair loss.

With the discovery of the possible link to PGD2 receptors, the drug was acquired by Kythera, and trials began to test the effects of setipiprant on hair loss.

1) Use for treatment of hair loss
2) For the treatment of benign prostatic hyperplasia, enlarged prostate shrink, improve urinary flow and improvement of benign prostatic hyperplasia caused symptoms.

Related Cosmetic Products 

Shanghai Biolang Biological  Co.,Ltd located in the Shanghai Zhangjiang BioPark where is a  High-tech Medical industry of China,specilize in producing and developing Sarms, peptide and antipsychotics raw materials in distributing the products of our own company and affiliated enterprises. We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the 25 years. 

Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

FAQ

Q: How to start orders or make payments?

A:You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

Q: How to confirm the Product Quality before placing orders?

A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q: What's your MOQ?

A:For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts from 100g and 1kg.

Q: Is there a discount?

A: Yes, for larger quantity, we always support with better price.

Q:How do you treat quality complaint?

First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q:How to contact us ?

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