Tiamulin is a semi-synthetic derivative of Pleuromutilin. It is highly active against gram-positive organisms such as streptococci,staphylococci and against mycoplasmas and serpulina (Treponema) hyodysenteriae. A number of Shigella, Klebsiella and E.coli are also quite susceptible to this agent. Some anaerobic species including Bacteroides fragilis and Clostridiumperfringens with no exception are sensitive to tiamulin.Tiamulin acts bacteriostatically. The biochemical basis for the antibacterial action is inhibition of protein synthesis, by binding to70S ribosomes.

Tiamulin is used for prevention and control of mycoplasmal diseases such as enzootic pneumonia and chronic respiratorydisease in pigs and poultry; and swine dysentery, porcine colonic spirochaetosis and porcine proliferative enteropathy.

Tiamulin is a semi-synthetic derivative of Pleuromutilin. It is highly active against gram-positive organisms, mycoplasmas and serpulina (Treponema) hyodysenteriae.

Tiamulin is used for prevention and control of mycoplasmal diseases such as enzootic pneumonia and chronic respiratory disease in pigs and poultry; swine dysentery, porcine colonic spirochaetosis and porcine proliferative enteropathy.