137-58-6 Factory Supply Best Price Local Anesthesia Lidocaine Powder CAS 137-58-6, Lidocaine Hydrochloride Lidocaina HCl Lidocaine CAS 73-78-9
China 137-58-6 Factory Supply Best Price Local Anesthesia Lidocaine Powder CAS 137-58-6, Lidocaine Hydrochloride Lidocaina HCl Lidocaine CAS 73-78-9, Find details about China 137-58-6, Lidocaine from 137-58-6 Factory Supply Best Price Local Anesthesia Lidocaine Powder CAS 137-58-6, Lidocaine Hydrochloride Lidocaina HCl Lidocaine CAS 73-78-9
Lidocaine
Lidocaine structure  | Common Name | Lidocaine | ||
|---|---|---|---|---|
| CAS Number | 137-58-6 | Molecular Weight | 234.337 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 372.7±52.0 °C at 760 mmHg | |
| Molecular Formula | C14H22N2O | Melting Point | 66-69°C | |
| MSDS | ChineseUSA | Flash Point | 179.2±30.7 °C | |
| Symbol | GHS07 | Signal Word | Warning | |
Use of LidocaineLidocaine, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.Target: Lidocaine is a common local anesthetic and antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery. Lidocaine, the first amino amide-type local anesthetic, was first synthesized under the name xylocaine by Swedish chemist Nils Lofgren in 1943. His colleague Bengt Lundqvist performed the first injection anesthesia experiments on himself.Lidocaine is approximately 95% metabolized (dealkylated) in the liver by CYP3A4 to the pharmacologically-active metabolites monoethylglycinexylidide (MEGX) and then subsequently to the inactive glycine xylidide. MEGX has a longer half life than lidocaine but also is a less potent sodium channel blocker. The elimination half-life of lidocaine is approximately 90-120 minutes in most patients. This may be prolonged in patients with hepatic impairment (average 343 minutes) or congestive heart failure (average 136 minutes). |
Lidocaine, an amide local anesthetic, has anti-inflammatory properties in vitro and in vivo, possibly due to an attenuation of pro-inflammatory cytokines, intracellular adhesion molecule-1 (ICAM-1), and reduction of neutrophils influx.Target: Lidocaine is a common local anesthetic and antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery. Lidocaine, the first amino amide-type local anesthetic, was first synthesized under the name xylocaine by Swedish chemist Nils Lofgren in 1943. His colleague Bengt Lundqvist performed the first injection anesthesia experiments on himself.Lidocaine is approximately 95% metabolized (dealkylated) in the liver by CYP3A4 to the pharmacologically-active metabolites monoethylglycinexylidide (MEGX) and then subsequently to the inactive glycine xylidide. MEGX has a longer half life than lidocaine but also is a less potent sodium channel blocker. The elimination half-life of lidocaine is approximately 90-120 minutes in most patients. This may be prolonged in patients with hepatic impairment (average 343 minutes) or congestive heart failure (average 136 minutes).
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 372.7±52.0 °C at 760 mmHg |
| Melting Point | 66-69°C |
| Molecular Formula | C14H22N2O |
| Molecular Weight | 234.337 |
| Flash Point | 179.2±30.7 °C |
| Exact Mass | 234.173218 |
| PSA | 32.34000 |
| LogP | 3.63 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.512 |
| Storage condition | Store at RT |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Water Solubility | practically insoluble |
1. Stored in a clean, cool and dry area; keep away from strong, direct light.
2. Shelf Life is 2 years when properly stored.
Packing:
1. Inner double plastic bags----25kg/Fiber drum (36*36*45cm, GW: 28kg, NW: 25kg);
2. Inner double plastic bags----5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg).
3. Inner double plastic bags----1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
P.S.: we accept packaging customization.
Delivery:
1. In stock products are normally shipping within 3 working days.
2. For rush delivery, please contact our sales team for particular arrangement
Shipping:
1. We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
2. Shipping details & shipping documents will be provided and sent by email.
3. We keep tracking the shippment until clients well received.
4. After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.
Hot sell products:
| CHEMICAL NAME | CAS No. | STATE | PRICE | FREE SAMPLE |
| Benzocaine | 94-09-7 | IN STOCK | Negotiable | Available |
| Benzocaine HCI | 23239-88-5 | IN STOCK | Negotiable | Available |
| Lidocaine | 137-58-6 | IN STOCK | Negotiable | Available |
| Lidocaine hydrochloride | 73-78-9 | IN STOCK | Negotiable | Available |
| Tetracaine | 94-24-6 | IN STOCK | Negotiable | Available |
| Boric acid | 11113-50-1 | IN STOCK | Negotiable | Available |
| Levamisole (hydrochloride) | 16595-80-5 | IN STOCK | Negotiable | Available |
| Procaine (HCI) | 51-05-8 | IN STOCK | Negotiable | Available |
| Procaine | 59-46-1 | IN STOCK | Negotiable | Available |
Payment term:
We accept various payment terms, the main methods are : T/T, L/C, Western Union, credit card, Bitcoin, USDT etc.
Shipping term:
WHY CHOOSE US
MU LEI (Wuhan) is committed to helping clients reach their goals, to providing high quality products and efficient shipments.
Our strong sense of responsibility with client projects means that we are constantly striving to provide solutions, even for issues they aren't yet aware of.
This sense of responsibility also means we value and promote seamless interaction with clients, and ensure the best value is obtained from their research budget.
Our staff bring professional knowledge to clients, as well as efficient responding to the clients, have built long-term cooperated relationships.
QWhat's your advantage?
AThe series of natural extracted product are all self-developed, produced and tested. Mature production technology, strict quality management system and cost control system, ensure the product stability and competitive price.
QHow to deal with quality complaints or the goods get loss?
AFirstly, every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA (or depends on customers' request).
If it is our product quality issue or due to the force majeures, we will send you another shipment for free.
QIs there any discount?
AThe price is negotiable. The more bigger quantity you order, the more competitive price you would get.
QHow do you manage the delivery?
AGoods will be shipped within 24 hours (Chinese public holiday are excluded), usually shipping by DHL, Fedex, EMS, TNT, HKETK. We will ship with the special safe channel to ensure you getting goods on time.QHow to place an order?
AInquiry + payment + shipping.
Firstly, please send inquiry infor to us, including quantity, your target price, shipping method, packing request, destination etc. We will reply you the quotation and lead time within 1-8 hours (different time zone).
Second, pay for the order, we accept various payment terms, the main methods are: T/T, L/C, Western Union, credit card, BitCoin, USDT, Money Gram.
After received the payment, we will ship out products immediately and share tracking number with you.
And for sure, we keep tracking the shippment, and we provide after-service.
QCan I get some samples?
AWarmly welcome, we can provide samples for free, but the shipping cost will be covered by customers.
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