Products

Weight Loss Raw Materia Orlistat CAS 96829-58-2 Treating Obesity Slimming

China Weight Loss Raw Materia Orlistat CAS 96829-58-2 Treating Obesity Slimming, Find details about China CAS 96829-58-2, Orlistat from Weight Loss Raw Materia Orlistat CAS 96829-58-2 Treating Obesity Slimming

Model NO.
CAS 96829-58-2
Origin
China
HS Code
29239000
Model NO.
CAS 96829-58-2
Origin
China
HS Code
29239000
Orlistat is a drug designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet. Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini. However, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug. The effectiveness of orlistat in promoting weight loss is definite but modest. Pooled data from clinical trials suggest that people given orlistat in addition to lifestyle modifications, such as diet and exercise, lose about 2-3 kilograms (4.4-6.6 lb) more than those not taking the drug over the course of a year. Orlistat also modestly reduces blood pressure and appears to prevent the onset of type 2 diabetes, whether from the weight loss itself or to other effects. In a large randomized controlled trial, orlistat was found to reduce the incidence of diabetes by nearly 40% in obese people.
Functions & Applications
Functions:
 
Orlistat capsula is in a class of drugs called lipase inhibitors. Orlistat capsula works in your intestines, where it blocks some of the fat you eat from being absorbed and digested. This undigested fat is then removed in your bowel movements .
 
Application:
 
1. As pharmaceutical raw materials 2. Health care products. 3. Orlistat capsula is used with a low-calorie diet to help you lose weight and to maintain your weight after weight loss.
ItemRequirementsTest Results
Appearancewhile to off-while powderWhite powder
IdentificationHPLC retention timeConforms
Melting Point42 ºC -45°C42°C-44°C
Specific optical rotation-31.0°~-41.0°-36.0°
Purity by HPLCno less than 98.0%98.5%
Total impurityno more than 2.0%1.6%
Max Individual impurityno more than 0.5%0.3%
Water content%(K&F)no more than 0.5%0.1%
Residual solventsEtOH no more than 0.5%N.D
EtAC no more than 0.5%N.D
nHeptane no more than 0.5%less than 0.1%
Residue on ignitionless than 0.2%0.10%
Assay (HPLC)no less than 98.0%98.60%
ConclusionMeets the Requirements

You Might Also Like