China API Anti-Cancer Raw Material Gefitinib 184475-35-2 with High Quality, Find details about China Gefitinib, 184475-35-2 from API Anti-Cancer Raw Material Gefitinib 184475-35-2 with High Quality
Product description
Gefitinib is an antineoplastic target therapy drug with relatively high specificity that was developed by the British pharmaceutical company AstraZeneca; it is the first molecular targeted drug to be used in non-small cell lung cancer treatment. Epidermal growth factors (EGF) are a kind of polypeptide with a relative molecular mass of 6.45x103, and they can bind with epidermal growth factor receptors (EGFR) on target cell membrane surfaces to trigger biological effects. EGFR is a type of tyrosine kinase (TK) type receptor, so when bound with EGF, it will promote TK activation in the receptor. This will cause tyrosine residue in the receptor to autophosphorylate and send continuous dividing signals into the cell, causing cell proliferation and differentiation. EGFR is abundant in human tissue, and it is highly expressed in malign tumors. Gefitinib blocks the signal transduction pathway of cell surface EGFR to prevent tumor growth, metastasis, and growth in blood vessels, and it can induce tumor cell apoptosis. Gefitinib is mainly used to treat non-stem cell lung cancer.
Melting point | 119-1200C |
Boiling point | 586.8±50.0 °C(Predicted) |
Density | 1.322±0.06 g/cm3(Predicted) |
Storage temp. | room temp |
Pka | 7.00±0.10(Predicted) |
Form | powder |
Color | white to beige |
About us
Packaging & Shipping
Shipping Terms | ||
By Express | By Air | By Sea |
Suitable for under 50kg Fast: 3-7 days Door to door service, easy to pick up the goods | Suitable for more than 50kg Fast: 3-7 days High cost Port to port, professional broker needed | Suitable for more than 500kg Slow: 7-45 days Low cost Port to port, professional broker needed |
Our Advantage
1.Any inquiry or message will be replied within 12 hours.
2.Professional manufacturer. Welcome to visit our website.
3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
4.Fast delivery.
5.After-sale services
FAQ
Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.
Q2. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Q3. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.
Q4. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
Q5. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.
Q6. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.
Q7. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
Q8.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.