High Quality API Powder Gefitinib Hydrochloride From Biocar

Chemical Information
 
Description

The EGFR is a Mr 170,000 transmembrane glycoprotein with an external binding domain and an intracellular tyrosine kinase domain. Gefitinib (ZD-1839, Iressa) is an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor.
Gefitinib inhibited colony formation in soft agar in a dose dependent manner in all cancer cell lines. However, treatment with higher doses resulted in a 2-4-fold increases in apoptosis. Dose-dependent supra-additive increase in growth inhibition was observed when cancer cells were treated with totoxic drugs and Gefitinib. The combined treatment markedly enhanced apoptotic cell death induced by single agent treatment.
Gefitinib treatment of nude mice bearing established human GEO colon cancer xenografts revealed a reversible dose-dependent inhibition of tumor growth because GEO tumors resumed the growth rate of controls at the end of the treatment.



Dosage 

Administration of a 250-mg dose of gefitinib as a dispersion preparation by drink or nasogastric tube achieved a systemic exposure to gefitinib that was consistent with that achieved when gefitinib was administered as a whole tablet. No evidence of tolerability problems associated with the routes of administration studied was observed in these healthy volunteers. 



FAQ
Order Guide

Q1: Have your Product Quality been Approved by the Third Party Lab?
A: Yes, all the products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2: How do you treat quality complaint?
A: First of all, our QC department will do the strict examination of our export products by HPLC, UV, GC , 
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem, caused by us, we will send you free goods for replacement or refund your loss.
 
Q3: Do you Accept Sample Order?
A: Yes, we can accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for the larger quantity, we always support with better price for our further cooperation. 

Q5: Do you accept VISA business credit card?
A: Sorry we don't accept VISA credit card, but we'd like to accept the bank transfer, Western Union, Paypal or Bitcoin.

Q6: How long does it take the goods to arrive?
It is Depending on your location,
For the small order, please expect the 5-7 days by DHL,UPS,TNT, FEDEX, EMS and so on.
For the mass order, please allow the 5-8 days by Air or 20-35 days by Sea.

Q7: Do you have any reshipment policy?  
Of course, we have the good after-sale service and re-shipment policy if the parcel lose.
Our long association with our clients has brought great benefits, we always take the upmost care in the packaging of our products. Our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts, it is still possible will seize a small number of packages. In this circumstance we promise reship free to establish a long term relationship with each other.
 
Q8: Can I get a sample?
A: Of course. For most products, we can provide you a free sample to test the quality, while the shipping cost should be undertook by your side.
We have formed a technology and management team that cooperate closely with some overseas Labs all speak highly of our safe shipping and goods.
please do not hesitate to contact us.