Best selling Setipiprant 866460-33-5 Pharmaceutical Raw Materials for Anti Hair Loss

 

Product name	Setipiprant
CAS No.	866460-33-5
Molecular Formula	C24H19FN2O3
Molecular Weight	402.4176632
Purity	99%

  Setipiprant Powder (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.

However, following the discovery in 2012 that the prostaglandin D2 receptor (DP/PGD2) is expressed at high levels in the scalp of men affected by male pattern baldness, the rights to setipiprant were acquired by Kythera with a view to potentially developing this drug as a novel treatment for baldness, with a previously unexploited mechanism of action. While it is too early to tell whether setipiprant will be an effective treatment for this condition, the favorable pharmacokinetics and relative lack of side effects seen in earlier clinical trials mean that fresh clinical trials for this new application can be conducted fairly quickly.

A phase 2A study is underway to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo and the active comparator, finasteride, in 18 to 41 years old males with androgenetic alopecia.

 

Hongkong XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.

superiority of choosing our company

1, We guarantee deeply analyze and demonstrate, purity more than 99%
2, Factory outlet with priority price & large stock.
3, Special magic vacuum safe package & safe shipping way.All parcel shipments are shipped discreetly and secure under customers' all requests.
4, We promise reship policies if post failed or refund if you need.
5, Rate of passing customs is 99.9% including Russia,Australia and anyother.
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Our services
1. Customer Satisfaction is our priority and guarantee for the future.
2. We co-develop products and projects with our partners.
3.Place of Origin China with Super quality by reasonable price.
4.When you meet problems in mineral processing, we can provide technical guidance.
5.We will ship the goods that you order from us by EMS, DHL, UPS, or FedEx.We will decided to choose which courier depend on Different countries.To find the best way to delivery the goods for you.
6.We will ship the goods within 5days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment...So we both can make the best of the bad bargain.
Bulk Order: Shipped via sea or air, it's according to your requirement, delivery time is 7-15days after payment
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We pride ourself on our excellent team of well-known engineers, technological persons and young professional staffs to research and develop new process. We are also dedicated to provide custom synthesis and contract research services to industrial and academic entities on a short or long-term basis. In our lab and pilot-plant, compounds can be manufactured in the quantity from a few grams up to tens of kilos and beyond. we can supply the key intermediates for your project, which short your synthesis scheme and supply you a reference compound for bioassay or a high purity analytical standard.