Chlorpheniramine maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an is chemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.

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Shaanxi Jeujon Bio-Tech LTD is located in Xi'an City, Shannxi Province, China. Now it is the leading researcher and one of the biggest manufacturer in both Pharmaceutials and high technology chemicals area. Jeujon is specialized in Research, Production, Process and Sales. We have absolute advantage because of strong research strength, modern management system and high-quality marketing team.There are 20 experts in our research team. We insist in innovation and produce high quality products. And we have GMP standard workshop and complete stainless extraction equipment. The superior product quality is guaranteed by 300,000 level air-conditioning clear system within purification, drying and packing procedures. We have 2 sales departments over 30 people and sell our products all over the world.We also have strong professional research and development team, talented personnel and completely equipped laboratory for the quality controlling. Various Detection Device is equipped in Jeujon, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, melting point apparatus and so on.
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