Top Quality Pharmaceutical Raw Material Sulfadoxine Powder Factory Direct Supply Product Name | Sulfadoxine |
CAS NO | 2447-57-6 |
Application | Pharmaceutical intermediates |
Appearance | White crystalline Powder |
Transportation | Sea,Air |
Molecular Weight | 310.33 |
Molecular Formula | C12H14N4O4S |
Melting Point | 190-194°C |
Boiling Point | 298°C (rough estimate) |
Density | 1.4006 (rough estimate) |
Storage | 2-8°C |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 522.8±60.0 °C at 760 mmHg |
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Melting Point | 190-194ºC |
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Molecular Formula | C12H14N4O4S |
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Molecular Weight | 310.329 |
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Flash Point | 270.0±32.9 °C |
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Exact Mass | 310.073578 |
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PSA | 124.81000 |
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LogP | 0.34 |
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Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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Index of Refraction | 1.623 |
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Water Solubility | Soluble in ethanol & ammonium hydroxide (9:1) at 20mg/ml |
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What is Sulfadoxine ?
Sulfadoxine is a sulfonamide antibiotic which inhibits enzymes that are essential in the production of folic acid (sc-204758) in parasites which cause malaria. Studies indicate that the parasite Plasmodium falciparum can utilize folic acid exogenously, which would resist the effects of Sulfadoxine. In order to prevent this resistance to Sulfadoxine, research has determined that the use of pyrimethamine (sc-208190) is required to inhibit the growth of this protozoan parasite. Suitable for people who are allergic to penicillin G and erythromycin, can treat respiratory infections, urinary system infections, soft tissue infections, tonsillitis, and diarrhea. In addition, it works for malaria, tuberculosis and leprosy.
Peripheral sulfonamides have strong antibacterial activity against hemolytic Streptococcus, pneumococci, Shigella, Staphylococcus aureus, E. coli, amphoteric bacteria, copper-green pseudocell bacteria, and salmonella. In addition, episodic sulfonamides also have antimalarial parasite effects.
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