CAS 6402-23-9 Rivanol
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Details of CAS 6402-23-9 Rivanol
Basic Info
Product Name:Ethacridine lactate monohydrate,Ethacridine Lactate
CAS NO.:6402-23-9
Molecular Formula:C18H23N3O5
Molecular Weight:361.39
Purity:99%
Appearance:Yellow Crystal
Grade:Pharmaceutical Grade
Ethacridine lactate (ethacridine monolactate monohydrate, acrinol, trade name Rivanol) is an aromatic organic compound based on acridine. Its formal name is 2-ethoxy-6,9-diaminoacridine monolactate monohydrate. It forms orange-yellow crystals with a melting point of 226 °C and it has a stinging smell.
Its primary use is as an antiseptic in solutions of 0.1%.
Ethacridine is also used as an agent for second trimester abortion. Up to 150 ml of a 0.1% solution is instilled extra-amniotically using a foley catheter. After 20 to 40 hours, 'mini labor' ensues. In China, an intra-amniotic method has also been used. Ethacridine as an abortifacient is found to be safer and better tolerated than 20% hypertonic saline.
Description
Rivanol is a lactic acid salt hydrate of α-ethoxy-6,9-diaminoacridine,which is a topical bactericidal and antiseptic. It has a strong killing effect on Gram-positive bacteria and a few Gram-negative bacteria, The antibacterial effect of cocci, especially streptococcus, and strong activity in alkaline environment. This product is irritant, the treatment concentration of normal tissue without damage, but it can stimulate uterine smooth muscle contraction, softening, relaxation of the cervix, it can be used for women in the induction of labor in the second trimester, no obvious side effects.
Usage And Dosage
1. A variety of trauma, skin mucosal exudate, erosion and infection Wound: 0.1% to 0.3% solution washing or wet wound infection wounds; or 0.1%, 0.5% ointment for external application of the wound.
2. Induction of labor in the second trimester: 0.2% of the injection with the product configuration (available sterile diluted with water for injection) by the lower abdominal wall for amniotic cavity injection, pregnancy 20 weeks or more for each 10 ml, less than 20 weeks of pregnancy each time 5 ml.
A dose of up to 50~100 mg, but the maximum amount of 120 mg. About 42 hours after the general drug output, more than 48 hours did not produce those who need to inject a second or switch to other methods; can also be used fetal membrane injection, the catheter to the uterine cavity by injecting 0.1% solution 50 ml , Keep the catheter removed after 24 hours.
ITEMS | SPECIFICATIONS | RESULTS |
Appearance | Yellow crystalline powder | Yellow crystalline powder e |
Identification | A. Infrared absorption | Positive |
B. The absorb of infrared spectrogram is comply with compared spectrogram | Comply | |
C. Conform to standard | Comply | |
D Conform to standard | Comply | |
Chloride | ≤0.025% | ≤0.025% |
Sulphate Ash | ≤0. 5% | ≤0. 5% |
Heavy metals | ≤0.003% | <0.003% |
Loss on drying | 4.5%~5.5% | 5.3% |
The related | The single of impurity ≤0.3% | 0.04% |
substance | The total impurities ≤1.0% | 0.07% |
Residue on ignition | ≤0.1% | 0.07 |
Assay | ≥ 99% | 99.8% |
Conclusion: | Comply with the CP2010 standard | |
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Thanks for your considering of Hebei Guanlang Biotechnology Co., Ltd.(Crovell). Crovell is a fast growing intermediates company,Which located in Shijiazhuang,Hebei Province.
Crovell is specialized in pharmaceutical intermediates, veterinary drug intermediates and dyes intermediates,such as phenylacetamide, dimethylamine hcl, benzyl chloride etc., Crovell also supply various industrial chemicals for customers, such as citric acid,potassium chloride etc.
After ten years development,Crovell has become a Diversified development company,not only involves in chemicals, but also real estate ,clothes ,agricultural products and so on.
So far, Crovell has business in more than 35 countries,most big customers come from europe and America, because among the suppliers in china,Crovell can always make the product quality best, some of the products from Crovell can reach the purity of 99.9+, such as 2-phenylacetamide. This is the important reason for customers who choosing Crovell.
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Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag outside and double plastic bag inside
Delivery Detail: within 10 days when get the payment.
Shipping :
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