China Pharma Grade Peptide Liraglutide API Pluma Liraglutide, Find details about China Liraglutide, Liraglutide Injection from Pharma Grade Peptide Liraglutide API Pluma Liraglutide
Basic Information
Liraglutide is a GLP-1 analog with 97% sequence homology to human GLP-1, which binds to and activates the GLP-1 receptor. The GLP-1 receptor is a target of native GLP-1, an endogenous incretin hormone that promotes glucose concentration-dependent secretion of insulin in pancreatic beta cells. Unlike Daran GLP-1, the pharmacokinetic and pharmacodynamic characteristics of liraglutide in humans are suitable for once-daily dosing regimens. After subcutaneous injection, the mechanism of prolonged action includes: self-association that slows down absorption; binding to albumin; and dipeptidyl peptidase IV (DPP-IV) and neutral endopeptidase (NEP) Higher enzyme stability and thus longer plasma half-life.
Product Name | Liraglutide |
Cas No. | 204656-20-2 |
Sequence | H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(N-ε-(Nα-Palmitoyl-L-γ-glutamyl))-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH |
Molecular Formula | C172H265N43O51 |
Molar Mass | 3751.202 g/mol |
Purity | ≥98% |
Impurity | ≤0.5% |
Storage Temperature | 2-8ºC |
Packing Size | 1G/Bottle, 10G/Bottle,50G/Bottle or at customers reqirement. |
APPLICATION&FUNCTION
Liraglutide improves control of blood glucose.It reduces meal-related hyperglycemia (for 24 hours after administration) by increasing insulin secretion (only) when required by increasing glucose levels, delaying gastric emptying, and suppressing prandial glucagon secretion.
1.It acts in a glucose-dependent manner, meaning it will stimulate insulin secretion only when blood glucose levels are higher than normal, preventing ""overshoot"". Consequently, it shows negligible risk of hypoglycemia.
2.It has the potential for inhibiting apoptosis and stimulating regeneration of beta cells (seen in animal studies).
3.It decreases appetite and inhibits body weight gain, as shown in a head-to-head study versus glimepiride.
4.It lowers blood triglyceride levels.
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FAQ & Payment
Question 1:Can you supply free samples ?
Answer:Because so many free sample orders everyday to us, sorry, we need to supply sample with charge,
but sample charge can be deducted from future orders.Hope you can understand.
Question 2: How to assure your delivery same good quality as sample?
Answer: We just take sample from mass production. So same production line,same quality.
Even we can supply you preshipment batch sample approval.
Question 3:What kind of payment do you prefer?
Answer: We can accept TT, LC,Westunion etc.
Payment Term | T/T | 30% T/T in advance, paid the balance before shipment | |
CFR(C&F) | |||
30% T/T in advance, paid the balance against copy of B/L | |||
CIF | |||
L/C | L/C amount above 20,000 usd, we can accept L/C at sight after the issuing bank approved by us | ||
West Union | |||
Amount lower than 5000usd |
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