Ranitidine hydrochloride is a inhibits production.It is commonly used in treatment of disease (PUD) and disease (GERD). Ranitidine is also used alongside and other antihistamines for the treatment of skin conditions such as . Ranitidine HCl is marketed under the brand name Zinetac or Zantac (not to be confused with or ).

Certain preparations of ranitidine are available (OTC) in various countries. In the United States, 75 mg and 150 mg tablets are available OTC. Zantac OTC is manufactured by . In Australia, packs containing 7 or 14 doses of the 150 mg tablet are available in supermarkets, small packs of 150 mg and 300 mg tablets are . Larger doses and pack sizes still require a prescription.

Outside of the United States, ranitidine is combined with (which acts as a mild ) as a salt (ranitidine bismuth citrate, Tritec), to treat infections. This combination is usually given with , an antibiotic.