Product Description:

        Terbinafine hydrochloride is a broad-spectrum antifungal acrylamine for dermatology developed by Novartis in the 1980s. It was first marketed in the UK in 1991 and was approved as an OTC drug by the US FDA in 1996. At present, it is sold in more than 90 countries worldwide It specifically interferes with the late biodecomposition of fungal Chemicalbook alcohols, selectively inhibits the activity of fungal squalene cycoxidase, so that the epoxidization reaction of squalene in the process of fungal cell membrane formation is blocked, so as to achieve the killing or inhibiting effect of fungi, which is suitable for the treatment of cutaneous candidiasis such as tinea hand, foot and jock Tinea of the body and tinea versicolor, also be the best medicamentum that treats gray nail.

    In 2000, terbinafine hydrochloride was included in the first batch of OTC catalogue published by the state. This product belongs to the antifungal class of drugs, it is right Shallow fungal infection has a strong effect, and topical use can cure most dermatomycosis.


    It has been reported that the peak plasma concentration of terbinafine hydrochloride was 0.97μg/ mL within 2 hours after administration of 250mg terbinafine hydrochloride. This product has an absorption half-life of 0.8 h and a dispersal half-life of 4.6 h. Its biological application is slightly affected by ingesting, but is not used for dose adjustment. The drug has a binding rate of 99% with plasma proteins, and can rapidly disperse through the dermis and concentrate in the lipophile cuticle Hair and skin in layers of fat can reach very high concentration Healing in the last few weeks, hy drochloric acid, naph thalene Finn to enter in the deck This product after the bioconversion of metabolites antifungal activity, they are secondary to remove its alleviation from urine has a half-life of 17 hours, no accumulation in the body, its steady blood drug concentration is not affected by age But liver The depletion rate of terbinafine hydrochloride can be reduced in persons with renal insufficiency, resulting in a decrease in blood concentration.

    1. Caused by Trichoderma alba, Trichoderma pedichii, Trichoderma verrucosa, Trichoderma trichoderma, Trichoderma purpura, etc., Microsporidia Canis and Trichoderma flocculum infections of the skin, hair and nail.

    2. Various tinea diseases (tinea corporis, tinea cruris, tinea capitis, etc.) and skin yeast infections caused by candida (candida albicans, etc.).

    3. Tinea chondria (nail fungal infection) caused by hair mold.

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