Factory Supply High Quality Inda Pamide Bp2021 CAS 26807-65-8

China Factory Supply High Quality Inda Pamide Bp2019 CAS 26807-65-8, Find details about China Pharmaceutical Product, Medical Chemical from Factory Supply High Quality Inda Pamide Bp2019 CAS 26807-65-8

Basic Info.

Model NO.

CAS 26807-65-8

Colour

White

Transport Package

25kgs Fiber Drum

Specification

BP2019

Origin

China

Model NO.

CAS 26807-65-8

Colour

White

Transport Package

25kgs Fiber Drum

Specification

BP2019

Origin

China

Product Desciption

Application:

Inda pamide has dual effects of diuresis and calcium antagonism. By inhibiting the reabsorption of Na+ at the proximal end of the distal convoluted tubules, inda pamide produces diuresis, and blocks Ca2+ influx. It has a high selectivity for vascular smooth muscle and expands peripheral small blood vessels. Produce a hypotensive effect. But the effect on vascular smooth muscle is stronger than diuretic effect. It can lower blood pressure when the dose is lower than the diuretic dose. It shows diuretic effect at higher doses, but it does not have the disadvantages of thiazide diuretics, that is, it does not cause orthostatic hypotension, flushing and reflex. Tachycardia has no significant effect on blood picture, blood lipids, glucose metabolism and renal function. The therapeutic dose has no significant changes on heart rate, cardiac output, and electrocardiogram, and has no significant effect on the central nervous system and autonomic nerves. Oral 2~3 Chemicalbookh produces a hypotensive effect, the effect is maintained for 24 hours, and the effect of single medication is good. The diuretic effect appeared in 3 hours, and reached the maximum effect in 4 to 6 hours. Different from other diuretics, this product is highly fat-soluble. After oral absorption, it has the highest plasma concentration in liver and kidney, and lower concentration in heart, lung, muscle, and fat. This product is mainly excreted from the kidneys as metabolites and 5% of the prototype. Indapa mide is suitable for mild and moderate essential hypertension, and can also be used for water and sodium retention caused by congestive heart failure. It is also suitable for hypertensive patients with renal failure, diabetes, and hyperlipidemia. It is used alone to reduce blood pressure The effect is significant, and the combination with β-blocker has better curative effect, because this medicine has diuretic effect and can cause hypokalemia, and potassium salt can be supplemented at the same time.
Factory Supply High Quality Inda Pamide Bp2019 CAS 26807-65-8