China GMP Factory Direct Supply 99% Purity Pramipexole HCl / Pramipexole Hydrochloride Powder CAS: 104632-25-9, Find details about China Pramipexole HCl, Pramipexole Hydrochloride Powder from China GMP Factory Direct Supply 99% Purity Pramipexole HCl / Pramipexole Hydrochloride Powder CAS: 104632-25-9
Product Name |
Pramipexole Hydrochloride |
Other Name |
Pramipexole HCl |
CAS NO: |
104632-25-9 |
Molecular Formular |
C10H19Cl2N3S |
EINECS NO |
226-500-0 |
MW |
206.24 |
Appearance |
white powder |
Place of origin |
China |
Pramipexole hydrochloride is a kind of drugs for treatment of Parkinson syndrome. It belongs to selective non-ergot dopamine receptor agonist. It was first successfully developed by Boehringer Ingelheim Company (Germany). It is a prescription drugs of dopamine receptor agonist applied in the largest amount of the world. In May, 1997, it had been approved for the first time by FDA for the treatment of idiopathic Parkinson's disease. It can reduce the symptoms and sign, and can either be used alone or in combination with levodopa. The trade name of the good marketed in the United States is Mirapex, which is the first drugs approved the FDA during the past six years for treatment of Parkinson syndrome. In 2007, it has entered into market in China with the commodity name being sifrol for the treatment of the signs and symptoms of idiopathic Parkinson's disease, being used either alone (without levodopa) or in combination with levodopa.
Items | Specification | Results |
Character | Off-white to white crystalline powder | Off-white crystalline powder |
Solubility | Soluble in Water and Methanol, slightly soluble in Ethanol (96%), Almost insoluble | Complies |
Identification | Specific Rotation -67-69.5° (on anhydrate basis) | -67.4 |
(2) IR:Meets the requirement. | Complies | |
(3) Optical purity Test | ||
(4) Chloride Reaction | ||
Clarity | Clear,not deeper than Y6. | |
PH | 2.8-3.4 | 2.9 |
Related Substances | Impurity A≤0.15% | 0.03% |
Impurity B≤0.15% | Not detected | |
Impurity C ≤0.15% | 0.04% | |
Unknown single impurity ≤0.15% | 0.07% | |
0.1% Total Impurity≤0.5% | 0.18% | |
Impurity D | Impurity D≤0. 5% | 0.05% |
Water | 4.5%-6.5% | 5.7% |
Heavy metals | ≤10ppm | complies |
Sulfate Ash | ≤0.1% | 0.04% |
Assay | 99.0%~101.0% | 99.4% |
Pramipexole Hydrochloride Powder,Pramipexole Dihydrochloride Powder,Pramipexole HCL Powder,Pramipexole Hydrochloride Powder, Pramipexole Dihydrochloride Monohydrate Manufacturer